Factors affecting time until myocardial infarction in hypertension patients using truncated Cox regression

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HOSSEINNATAJ ABOLFAZL; YAZDANI CHARATI JAMSHID; MOHSENI POUYA HOSSEIN; GHAEMIAN ALI; Nikaein Roja; BAGHERI MOHAMMAD

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Journal Paper

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Journal: Journal of Shahrekord University of Medical Sciences Year:2019 | Volume:21 | Issue:4 Page(s): 169-174

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Title

Factors affecting time until myocardial infarction in hypertension patients using truncated Cox regression

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Keywords

Hypertension

Truncated Cox regression

Myocardial infarction

Survival time

Abstract

Background and aims: Hypertension is one of the most common and important risk factors of cardiovascular diseases. This phenomenon, if not cured, causes lots of problems in vital organs of the body like kidneys, brain, eyes, and heart. The aim of the current study was to identify factors which affect the time until Myocardial infarction (MI) in Hypertension patients using Truncated Cox regression. Methods: This study was a population retrospective cohort and its statistical population included patients with Hypertension symptoms, who had MI for the first time in Sari. A decision was made based on continuing the study as a nested case and control study because the number of MI incidents was low (7%) in the studied sample. In addition, the Cox’ s model and truncated Cox were used for determining the factors affecting the patients’ survival. Results: The median and mean Survival times in this sample were equal to 57 and 66. 44 months, respectively. Considering time truncation, family history (HR=1. 70) and the age at diagnosis (HR=0. 99) were statistically significant in the Cox’ s model (P< 0. 05). Conclusion: Overall, using the Akaike criterion for comparing the Survival time without the effect of truncation, the Cox’ s model demonstrated better fitness by controlling the truncation effect. These results show the importance of controlling the truncation in those diseases in which it is impossible to distinguish the time of the appearance from the symptoms.

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APA: Copy

HOSSEINNATAJ, ABOLFAZL, YAZDANI CHARATI, JAMSHID, MOHSENI POUYA, HOSSEIN, GHAEMIAN, ALI, Nikaein, Roja, & BAGHERI, MOHAMMAD. (2019). Factors affecting time until myocardial infarction in hypertension patients using truncated Cox regression. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 21(4), 169-174. SID. https://sid.ir/paper/766396/en

Vancouver: Copy

HOSSEINNATAJ ABOLFAZL, YAZDANI CHARATI JAMSHID, MOHSENI POUYA HOSSEIN, GHAEMIAN ALI, Nikaein Roja, BAGHERI MOHAMMAD. Factors affecting time until myocardial infarction in hypertension patients using truncated Cox regression. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;21(4):169-174. Available from: https://sid.ir/paper/766396/en

IEEE: Copy

ABOLFAZL HOSSEINNATAJ, JAMSHID YAZDANI CHARATI, HOSSEIN MOHSENI POUYA, ALI GHAEMIAN, Roja Nikaein, and MOHAMMAD BAGHERI, “Factors affecting time until myocardial infarction in hypertension patients using truncated Cox regression,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 4, pp. 169–174, 2019, [Online]. Available: https://sid.ir/paper/766396/en

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