Chronic Active Epstein-Barr Virus Infection in a Patient with Enteritis, Myositis, and Pericardial Effusion: A Case Report

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Huang Jin Xian; Huang Xiao Yan; Zhang Lijun; Wang Ya Qin

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Iranian Red Crescent Medical Journal Year:2020 | Volume:22 | Issue:7 Page(s): 0-0

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Title

Chronic Active Epstein-Barr Virus Infection in a Patient with Enteritis, Myositis, and Pericardial Effusion: A Case Report

Author(s)

Huang Jin Xian | Huang Xiao Yan | Zhang Lijun | Wang Ya Qin | Issue Writer Certificate

Keywords

Epstein-Barr Virus Infections

Enteritis

Myositis

Pericardial Effusion

Abstract

Introduction: Chronic active Epstein-Barr virus infection (CAEBV) is a rare, life-threatening disease entity involving multiple organs and systems. The disease could be presented in a single organ with atypical symptoms, be misdiagnosed at the early phase, and resolved without aggressive treatment. Previous studies reported favorable outcomes with early diagnosis and treatment, while in other cases, disease progressionandpresenting in other organs could result in a very poor outcome. Cliniciansfromanydepartment should be aware of the CAEBV entity when an unresolved systemic inflammation presents. Case Presentation: A 61-year-old female presented to the cardiology department due to edema and fatigue with the progression of symptoms, including fever, muscle weakness, andshortness of breath. MRimagesshowedmuscularedema, andultrasound analysis revealed massive Pericardial Effusion. Results of laboratory tests indicated hematological involvement, liver damage, and positivity for EBV DNA, and EBER in muscle and intestine by staining. She was first misdiagnosed with ulcerative colitis, but the disease evolved to the muscles and cardiovascular system later on. Altogether, the CAEBV infection with Enteritis, Myositis, and Pericardial Effusion was confirmed in the case. Although diagnosed, the treatment of the elderly population remains rather challenging in severe cases. The patient died after disease onset for less than three years. Conclusions: Elderly patients with CAEBV infection tend to have a poor prognosis. Early diagnosis would facilitate early treatment and the utilization of available options, which might reduce the disease mortality rate eventually. Individualized therapy and promising approaches should be further developed for CAEBV infection.

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APA: Copy

Huang, Jin Xian, Huang, Xiao Yan, Zhang, Lijun, & Wang, Ya Qin. (2020). Chronic Active Epstein-Barr Virus Infection in a Patient with Enteritis, Myositis, and Pericardial Effusion: A Case Report. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 22(7), 0-0. SID. https://sid.ir/paper/768385/en

Vancouver: Copy

Huang Jin Xian, Huang Xiao Yan, Zhang Lijun, Wang Ya Qin. Chronic Active Epstein-Barr Virus Infection in a Patient with Enteritis, Myositis, and Pericardial Effusion: A Case Report. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2020;22(7):0-0. Available from: https://sid.ir/paper/768385/en

IEEE: Copy

Jin Xian Huang, Xiao Yan Huang, Lijun Zhang, and Ya Qin Wang, “Chronic Active Epstein-Barr Virus Infection in a Patient with Enteritis, Myositis, and Pericardial Effusion: A Case Report,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 22, no. 7, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/768385/en

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