SEROEPIDEMIOLOGY OF VZV IN THE YOUNG ADULTS REFERRING TO RASOUL-AKRAM HOSPITAL IN TEHRAN

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TALEBI TAHER MAHSHID; REZAIE OMID

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Journal Paper

Paper Information

Journal: Scientific Journal of Kurdistan University of Medical Sciences Year:2012 | Volume:17 | Issue:1 (SERIAL NUMBER 63) Page(s): 36-42

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Information Journal Paper

Title

SEROEPIDEMIOLOGY OF VZV IN THE YOUNG ADULTS REFERRING TO RASOUL-AKRAM HOSPITAL IN TEHRAN

Author(s)

TALEBI TAHER MAHSHID | REZAIE OMID | Issue Writer Certificate

Keywords

VARICELLA ZOSTER VIRUS (VZV)Q2

CHICKEN-POXQ3

SERO-EPIDEMIOLOGYQ3

IRANQ2

Abstract

Background and Aim: Varicella-Zoster virus causes chicken - pox, which is a mild disease in children. However, in adolescents and adults between 20 to 40 years of age, it may be severe with visceral involvement such as pneumonia and hepatitis. In this study the level of anti VZV antibody in young adults was determined. Compatibility of the history of varicella with presence of varicella antibody in this population, considering sensitivity, specificity, predictive positive and predictive negative values, was assessed.Material and Methods: This cross–sectional study included 400 healthy young adults. The enzyme immunoassay was used to determine the titer of IgG antibodies against VZV in the sera. Statistical analysis of the data was performed by means of chi2 test.Results: A total of 400 young adults between 20 and 40 years of age were examined and 313 (78. 25%) of them were found to be seropositive. Sero-positivity was more significant in the females (P=0.048). There was no statistically significant difference in the antibody titer between different age groups (P=0.82). Correlations of sensitivity and positive predictive value of history of varicella with presence of antibody in the sera were 89% and 95% respectively.Conclusion: The results of this study showed a significant number of young adults are susceptible to infection and extensive screening and sero-prevalence studies are needed to make decision about mass vaccination in children in IRAN.

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APA: Copy

TALEBI TAHER, MAHSHID, & REZAIE, OMID. (2012). SEROEPIDEMIOLOGY OF VZV IN THE YOUNG ADULTS REFERRING TO RASOUL-AKRAM HOSPITAL IN TEHRAN. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 17(1 (SERIAL NUMBER 63)), 36-42. SID. https://sid.ir/paper/76854/en

Vancouver: Copy

TALEBI TAHER MAHSHID, REZAIE OMID. SEROEPIDEMIOLOGY OF VZV IN THE YOUNG ADULTS REFERRING TO RASOUL-AKRAM HOSPITAL IN TEHRAN. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;17(1 (SERIAL NUMBER 63)):36-42. Available from: https://sid.ir/paper/76854/en

IEEE: Copy

MAHSHID TALEBI TAHER, and OMID REZAIE, “SEROEPIDEMIOLOGY OF VZV IN THE YOUNG ADULTS REFERRING TO RASOUL-AKRAM HOSPITAL IN TEHRAN,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 1 (SERIAL NUMBER 63), pp. 36–42, 2012, [Online]. Available: https://sid.ir/paper/76854/en

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