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Information Journal Paper

Title

Comparison of the Effect of Intra-Rectal Administration of Lidocaine Gel and Lidocaine Plus Fentanyl on Pain Reduction in Prostate Biopsy: A Randomized Clinical Trial

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Abstract

 Objectives: The aim of this study was to compare the effect of intra-rectal administration of Lidocaine gel alone versus Lidocaine gel plus topical Fentanyl on Pain reduction in Prostate Biopsy. Methods: In a double-blind randomized clinical trial, 96 patients who met the inclusion criteria were randomly assigned into two groups. 1) The treatment group: Lidocaine gel (2%) 50 g and 2) the intervention group: Lidocaine gel (2%) 50 g and Fentanyl gel 50 µ g. During the Prostate Biopsy, the VAS score was recorded. Blood pressure, heart rate, and patient level of consciousness were also analyzed. Results: The mean VAS score was 5. 1 ± 2 and 3. 0 ± 2, which was lower in the intervention group (P value < 0. 001). In terms of consciousness after biopsy, there was no difference between the two groups (P value = 0. 358). There was no difference between the groups in terms of mean blood pressure and heart rate before and during the Prostate Biopsy. Finally, in terms of consciousness after the Prostate Biopsy, there was no difference between the current treatment and intervention groups. Conclusions: The combination of Lidocaine gel and Fentanyl with a dose of 50 µ g has a significant effect on reducing the Pain associated with Prostate Biopsy in comparison with Lidocaine gel alone. The antinociceptive effect of the above regimens is not associated with hemodynamic changes and changes in patients' consciousness.

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    APA: Copy

    IMANI, FARSAD, KHAJAVI, MOHAMMADREZA, Gavili, Tayeb, POURFAKHR, PEJMAN, SHARIAT MOHARARI, REZA, ETEZADI, FARHAD, & HOSSEINI, SEYED REZA. (2018). Comparison of the Effect of Intra-Rectal Administration of Lidocaine Gel and Lidocaine Plus Fentanyl on Pain Reduction in Prostate Biopsy: A Randomized Clinical Trial. ANESTHESIOLOGY AND PAIN MEDICINE, 8(6), 0-0. SID. https://sid.ir/paper/768948/en

    Vancouver: Copy

    IMANI FARSAD, KHAJAVI MOHAMMADREZA, Gavili Tayeb, POURFAKHR PEJMAN, SHARIAT MOHARARI REZA, ETEZADI FARHAD, HOSSEINI SEYED REZA. Comparison of the Effect of Intra-Rectal Administration of Lidocaine Gel and Lidocaine Plus Fentanyl on Pain Reduction in Prostate Biopsy: A Randomized Clinical Trial. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2018;8(6):0-0. Available from: https://sid.ir/paper/768948/en

    IEEE: Copy

    FARSAD IMANI, MOHAMMADREZA KHAJAVI, Tayeb Gavili, PEJMAN POURFAKHR, REZA SHARIAT MOHARARI, FARHAD ETEZADI, and SEYED REZA HOSSEINI, “Comparison of the Effect of Intra-Rectal Administration of Lidocaine Gel and Lidocaine Plus Fentanyl on Pain Reduction in Prostate Biopsy: A Randomized Clinical Trial,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 8, no. 6, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/768948/en

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