Evaluation of Efficacy of Razi Fowl Pox Vaccine in Comparison with the Commercial Fowl Pox Vaccine in SPF Chickens by Challenge Test

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Khalesi Bahamn; EBRAHIMI MOHAMMAD MAJID; Ghodsian Naser; Kaffashi Amir; SHAHKARAMI MOHAMMAD KAZEM; Ebrahimzadeh Mir Saeed

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Journal Paper

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Journal: Iranian Journal of Virology Year:2019 | Volume:13 | Issue:1 Page(s): 1-8

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Title

Evaluation of Efficacy of Razi Fowl Pox Vaccine in Comparison with the Commercial Fowl Pox Vaccine in SPF Chickens by Challenge Test

Author(s)

Keywords

Efficiency

fowl pox vaccine

Razi institute

challenge test

Abstract

Background and Aims: fowl pox vaccine is produced in the Razi institute for almost half a century and has a favorable and productive yield in poultry flocks and has provided complete satisfaction to the poultry breeder. In terms of comparing the efficacy of this vaccine with imported vaccines, the following research was conducted. Materials and Methods: In this study, based on the latest protocols of European Pharmacopeia and OIE, 100 SPF chicks were divided into five groups: the first group was given 20 SPF chickens at the age of 8 to 10 weeks of domestic vaccine (Razi institute: Live attenuated (inoculation in the wing with the needle of the twin branches); also in the second to fourth group: to 60 SPF chicks (in three groups of 20) at the age of 8 to 10 weeks; imported vaccines (I, C and H) were injected. Finally, in the fifth group, 20 chicks were considered as controls and did not receive vaccine. Response of the immune system was observed 7 to 10 days after vaccination by observing nodules at the injection site (Takes reaction). At 21 days (three weeks), all four groups vaccinated with acute pathogenesis of fowl pox strain were challenged. Chickens were observed daily for 21 days after vaccination and the results of vaccination immunization were evaluated and analyzed by statistical analysis. Results: The results of the experiments indicated that after vaccination, 100% of the vaccinated chickens were positive by takes responses and after being challenged in four groups vaccinated in the Razi, I, C vaccines 100% and vaccine H, 95% of the immune responses were observed lesions in the Crown of the birds, and in the control group, there were symptoms of cartilage like in 100% of the birds. Conclusions: In general, according to the OIE standard, the above experiments showed that fowl pox vaccine Razi institute induces high immunity and has efficacy similar to imported vaccines.

Cites

Evaluation and Optimization of Chick Embryo Fibroblasts for Production of a Fowl Pox Vaccine Based on Cell Culture

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APA: Copy

Khalesi, Bahamn, EBRAHIMI, MOHAMMAD MAJID, Ghodsian, Naser, Kaffashi, Amir, SHAHKARAMI, MOHAMMAD KAZEM, & Ebrahimzadeh, Mir Saeed. (2019). Evaluation of Efficacy of Razi Fowl Pox Vaccine in Comparison with the Commercial Fowl Pox Vaccine in SPF Chickens by Challenge Test. IRANIAN JOURNAL OF VIROLOGY, 13(1), 1-8. SID. https://sid.ir/paper/769231/en

Vancouver: Copy

Khalesi Bahamn, EBRAHIMI MOHAMMAD MAJID, Ghodsian Naser, Kaffashi Amir, SHAHKARAMI MOHAMMAD KAZEM, Ebrahimzadeh Mir Saeed. Evaluation of Efficacy of Razi Fowl Pox Vaccine in Comparison with the Commercial Fowl Pox Vaccine in SPF Chickens by Challenge Test. IRANIAN JOURNAL OF VIROLOGY[Internet]. 2019;13(1):1-8. Available from: https://sid.ir/paper/769231/en

IEEE: Copy

Bahamn Khalesi, MOHAMMAD MAJID EBRAHIMI, Naser Ghodsian, Amir Kaffashi, MOHAMMAD KAZEM SHAHKARAMI, and Mir Saeed Ebrahimzadeh, “Evaluation of Efficacy of Razi Fowl Pox Vaccine in Comparison with the Commercial Fowl Pox Vaccine in SPF Chickens by Challenge Test,” IRANIAN JOURNAL OF VIROLOGY, vol. 13, no. 1, pp. 1–8, 2019, [Online]. Available: https://sid.ir/paper/769231/en

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