Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

132
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

115
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

The Expression Levels of Matrix Metalloproteinases Inhibitors TIMP1, TIMP2 and Matrix Metalloproteinases MMP2, MMP9 in Iraqi Patients Diagnosed with Colon Cancer

Pages

  172-188

Abstract

 Background: Colon cancer is the third most common cancer worldwide, responsible for more than half a million deaths every year. Metalloproteinases (MMP2 and MMP9) participate in tumor invasion and metastasis because of their ability to degrade the extracellular matrix (ECM). Materials and Methods: The expression levels of MMP2 and MMP9 as well as tissue inhibitor metalloproteinases TIMP1 and TIMP2 were determined by Immunohistochemistry in 42 Iraqi patients diagnosed with Colon cancer as well as in 18 benign tissues. Results: Immunohistochemistry revealed that the protein expression levels of MMP2, MMP9, TIMP1 and TIMP2 increased by 83%, 72%, 64%, and 57%, respectively, in patients with Colon cancer tissues compared with 19%, 28%, 23%, and 16%, respectively, in benign tissues. Conclusion: MMP2, MMP9, TIMP1 and TIMP2 expression levels in Iraqi patients with Colon cancer could be used as potential markers that can predict tumor behavior, progression, and prognosis.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    Mahmood, Noah A., Abdulghany, Zaynab S., & Al Sudani, Israa M.. (2019). The Expression Levels of Matrix Metalloproteinases Inhibitors TIMP1, TIMP2 and Matrix Metalloproteinases MMP2, MMP9 in Iraqi Patients Diagnosed with Colon Cancer. GOVARESH JOURNAL, 24(3 ), 172-188. SID. https://sid.ir/paper/769691/en

    Vancouver: Copy

    Mahmood Noah A., Abdulghany Zaynab S., Al Sudani Israa M.. The Expression Levels of Matrix Metalloproteinases Inhibitors TIMP1, TIMP2 and Matrix Metalloproteinases MMP2, MMP9 in Iraqi Patients Diagnosed with Colon Cancer. GOVARESH JOURNAL[Internet]. 2019;24(3 ):172-188. Available from: https://sid.ir/paper/769691/en

    IEEE: Copy

    Noah A. Mahmood, Zaynab S. Abdulghany, and Israa M. Al Sudani, “The Expression Levels of Matrix Metalloproteinases Inhibitors TIMP1, TIMP2 and Matrix Metalloproteinases MMP2, MMP9 in Iraqi Patients Diagnosed with Colon Cancer,” GOVARESH JOURNAL, vol. 24, no. 3 , pp. 172–188, 2019, [Online]. Available: https://sid.ir/paper/769691/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top