Comparison of the Effects of Oral Sucrose 30% and 50% on the Pain of Injection of Hepatitis B Vaccine in Newborns

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IMANI ALI; MORADI FATEMEH

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Journal Paper

Paper Information

Journal: Zahedan Journal of Research in Medical Sciences Year:2020 | Volume:22 | Issue:1 Page(s): 0-0

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Information Journal Paper

Title

Comparison of the Effects of Oral Sucrose 30% and 50% on the Pain of Injection of Hepatitis B Vaccine in Newborns

Author(s)

IMANI ALI | MORADI FATEMEH | Issue Writer Certificate

Keywords

Infant Pain

Sucrose

Intramuscular Injection

Hepatitis B Vaccine

Abstract

Background: Uncontrolled pain in newborns results in permanent damage to the growth components of cognitive development and changes in response to subsequent painful stimuli. Objectives: The aim of this study was to comparison of the effects of oral Sucrose 30% and 50% on the pain of injection of Hepatitis B Vaccine in newborns. Methods: In these triple-blind clinical trial conducted at Amir-al Momenin Hospital in Semnan, 91 term infants were selected and randomly divided into three groups. Two minutes prior to Intramuscular Injection of Hepatitis B Vaccine in the case group, 2 mL of Sucrose solution 30% or 50% and in the control group the same volume of sterile water was given orally to the infant. Prior to the administration of Sucrose, immediately after injection and 5 minutes after injection the Neonatal Infant Pain Scale (NIPS) was used to assess pain. For statistical data analysis, Mann-Whitney, chi-square, Kruskal-Wallis, One-Way ANOVA and Dunnett tests at a significance level of 5% were used. Results: The results showed that Sucrose 30% and 50% significantly reduced pain during, immediately, and 5 minutes after injection (P < 0. 05). Conclusions: In general, high concentrations of Sucrose can relieve the pain of vaccination and can be used in the clinic.

Cites

EFFECTS OF ORAL 20% SUCROSE ON SEVERITY OF PAIN DURING VENIPUNCTURE IN PREMATURE NEONATES IN MOTAHARI HOSPITAL OF URMIA, IRAN, 2019-2020

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APA: Copy

IMANI, ALI, & MORADI, FATEMEH. (2020). Comparison of the Effects of Oral Sucrose 30% and 50% on the Pain of Injection of Hepatitis B Vaccine in Newborns. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 22(1), 0-0. SID. https://sid.ir/paper/773180/en

Vancouver: Copy

IMANI ALI, MORADI FATEMEH. Comparison of the Effects of Oral Sucrose 30% and 50% on the Pain of Injection of Hepatitis B Vaccine in Newborns. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2020;22(1):0-0. Available from: https://sid.ir/paper/773180/en

IEEE: Copy

ALI IMANI, and FATEMEH MORADI, “Comparison of the Effects of Oral Sucrose 30% and 50% on the Pain of Injection of Hepatitis B Vaccine in Newborns,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 22, no. 1, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/773180/en

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