The Effect of Fluid Therapy in Acute Post-operative Complications of Breast Cancer; Pain and Post-operative Nausea and Vomiting

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SOLEIMANI MOHSEN; MOHAMMADI MOHAMMAD; TEYMOURIAN HOUMAN; Gholizadeh Naeimeh; Khazaei Yasmin; SAFARI FARHAD

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Journal: International Journal of Cancer Management Year:2018 | Volume:11 | Issue:6 Page(s): 0-0

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Title

The Effect of Fluid Therapy in Acute Post-operative Complications of Breast Cancer; Pain and Post-operative Nausea and Vomiting

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Keywords

PONV

Pain

Crystalloid

Abstract

Background: Post-operative nausea and vomiting (PONV) still continues to be a serious problem. Incidence of PONV is more than 20% to 30%. Intravenous fluid administration seems to decrease PONV. Objectives: The aim of this study was to evaluate the effect of pre-operative and intraoperative intravenous hydration in comparison to routine hydration on PONV in breast cancer surgery. Methods: This study was performed on 105 female patients with ASA class grade I and II; they were randomly divided to 3; group 1: routine hydration (1. 5 cc/kg/h normal saline). Group 2: routine hydration + 5 cc/kg of ringer lactate serum 80 to 90 minutes before surgery, and group 3: routine hydration + 5 cc/kg post-operative Pain, anti-emetic and analgesic administration were compared between 3 groups, using VAS and cortila questionnaire. Results: There were no significant difference between 3 groups considering demographic data (age, literacy, weight, height, etc. ) duration of breast cancer, cancer stage, pre-operative fasting time, duration of surgery, etc. Blood loss was significantly lower in intraoperative fluid supplementation group (P < 0. 05), but PONV and post-operative Pain were significantly lower in those who received pre-operative fluid supplementation. They also needed less anti-emetic or analgesic administration. Conclusions: Pre-operative fluid supplementation showed to be an effective prophylactic strategy in PONV. Type of fluid and its volume need more evaluation in future studies.

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APA: Copy

SOLEIMANI, MOHSEN, MOHAMMADI, MOHAMMAD, TEYMOURIAN, HOUMAN, Gholizadeh, Naeimeh, Khazaei, Yasmin, & SAFARI, FARHAD. (2018). The Effect of Fluid Therapy in Acute Post-operative Complications of Breast Cancer; Pain and Post-operative Nausea and Vomiting. INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION), 11(6), 0-0. SID. https://sid.ir/paper/773209/en

Vancouver: Copy

SOLEIMANI MOHSEN, MOHAMMADI MOHAMMAD, TEYMOURIAN HOUMAN, Gholizadeh Naeimeh, Khazaei Yasmin, SAFARI FARHAD. The Effect of Fluid Therapy in Acute Post-operative Complications of Breast Cancer; Pain and Post-operative Nausea and Vomiting. INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION)[Internet]. 2018;11(6):0-0. Available from: https://sid.ir/paper/773209/en

IEEE: Copy

MOHSEN SOLEIMANI, MOHAMMAD MOHAMMADI, HOUMAN TEYMOURIAN, Naeimeh Gholizadeh, Yasmin Khazaei, and FARHAD SAFARI, “The Effect of Fluid Therapy in Acute Post-operative Complications of Breast Cancer; Pain and Post-operative Nausea and Vomiting,” INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION), vol. 11, no. 6, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/773209/en

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