EVALUATION OF RADIOSENSITIVITY OF HELA CELLS INFECTED WITH POLIO VIRUS IRRADIATED BY CO 60

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SEYF F.; KHEYR ELAH BAYATIANI M.R.; TAHMASBI BEYRGANI M.J.; ANSARI MANSOUR; SOHRABI AMIR; HOSSEINI F.A.S.

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Journal: Armaghane Danesh Year:2008 | Volume:13 | Issue:1 (49) Page(s): 89-95

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Title

EVALUATION OF RADIOSENSITIVITY OF HELA CELLS INFECTED WITH POLIO VIRUS IRRADIATED BY CO 60

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Keywords

RADIOSENSITIVITYQ3

HELA CELLSQ3

POLIO VIRUSQ3

Abstract

Introduction & Objective: The main purpose of radiotherapy is exposing enough doses of radiation to tumor tissue and protecting the normal tissues around it. Tumor dose for each session in radiotherapy will be considered based on RADIOSENSITIVITY of the tissues. The presence of viral diseases in tumoral area can affect the RADIOSENSITIVITY of cells. This study aimed to evaluate the RADIOSENSITIVITY of HELA CELLS infected with poliomyelitis virus irradiated by Co 60.Materials & Methods: In this study, the RADIOSENSITIVITY of HELA CELLS, with or without the viral infection, after gamma radiation of cobalt 60, was assessed.Results: Results of comparison of the radisensitivity of infected and uninfected cells indicates that after 2 Gy irradiation by Co 60, polio infection in low, moderate and high virus load, increases the cell death by 20-30%, 30-40% and 70-90% respectively. Conclusion: RADIOSENSITIVITY of tumoral cells increases when they are infected with viral agents. Results of this study showed that non cancer diseases should be considered when prescribing dose fraction in radiotherapy of cancers.

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APA: Copy

SEYF, F., KHEYR ELAH BAYATIANI, M.R., TAHMASBI BEYRGANI, M.J., ANSARI, MANSOUR, SOHRABI, AMIR, & HOSSEINI, F.A.S.. (2008). EVALUATION OF RADIOSENSITIVITY OF HELA CELLS INFECTED WITH POLIO VIRUS IRRADIATED BY CO 60. ARMAGHAN DANESH, 13(1 (49)), 89-95. SID. https://sid.ir/paper/77486/en

Vancouver: Copy

SEYF F., KHEYR ELAH BAYATIANI M.R., TAHMASBI BEYRGANI M.J., ANSARI MANSOUR, SOHRABI AMIR, HOSSEINI F.A.S.. EVALUATION OF RADIOSENSITIVITY OF HELA CELLS INFECTED WITH POLIO VIRUS IRRADIATED BY CO 60. ARMAGHAN DANESH[Internet]. 2008;13(1 (49)):89-95. Available from: https://sid.ir/paper/77486/en

IEEE: Copy

F. SEYF, M.R. KHEYR ELAH BAYATIANI, M.J. TAHMASBI BEYRGANI, MANSOUR ANSARI, AMIR SOHRABI, and F.A.S. HOSSEINI, “EVALUATION OF RADIOSENSITIVITY OF HELA CELLS INFECTED WITH POLIO VIRUS IRRADIATED BY CO 60,” ARMAGHAN DANESH, vol. 13, no. 1 (49), pp. 89–95, 2008, [Online]. Available: https://sid.ir/paper/77486/en

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