Evaluation of Antibiotic Resistance Trend among Cystic Fibrosis Patients: A Single Center Study from 2014-2019

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HASSANZAD MARYAM; Sadati Elham; GHORBANI FARIBA; GHAFARIPOOR HOSSEINALI; Farnia Poopak; POORABDOLLAH MIHAN; BAGHAEI NOUSHIN; EMAMI HABIB; VELAYATI ALI AKBAR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Pediatric Perspectives Year:2020 | Volume:8 | Issue:1 (73) Page(s): 10719-10729

Download Full-Text

View:

107

Download:

171

Cites:

Information Journal Paper

Title

Evaluation of Antibiotic Resistance Trend among Cystic Fibrosis Patients: A Single Center Study from 2014-2019

Author(s)

Keywords

Antibiotic Resistance

Cystic fibrosis

Drug resistance

Microbial culture

Abstract

Background: Antibiotic Resistance in Cystic fibrosis (CF) patients has been a serious issue in their survival. The objective of this study was to investigate the antibiogram trend in serial admissions among CF patients. Materials and Methods: In this retrospective descriptive-analytical study, from 2014 to 2019, 95 known cases of CF patients with repeated admissions at Masih Daneshvari Hospital, Tehran, Iran, were evaluated. Demographic data and para-clinical parameters were evaluated. Fourteen antibiotic disks were used to determine Antibiotic Resistance. Resistance trend in 2014 and 2018 was compared. Results: Out of 95 patients, 48 patients (52. 2%) were female. The mean age of patients was 19. 43 ± 6. 7 years. Pseudomonas positive culture in the first admission was 68. 4%; while it was 45. 3% in the second admission and 28. 4% in the third admission (p> 0. 05). Staph positive culture was 20%; 18. 9%, and 16. 8%, respectively (p> 0. 05). Pseudomonas aeruginosa was the most sensitive to vancomycin (93. 8%), followed by colistin (93. 3%) and ceftazidime (65. 2%). There was no correlation between patients' age and multiDrug resistance (MDR). FEV1 was significantly lower in both the patient with positive pseudomonas (p-value: 0. 01), and culture and MDR (p= 0. 023). Furthermore, in terms of Antibiotic Resistance over time, resistance to colistin statistically decreased from 25% in 2014 to 2% in 2018 (p= 0. 02). Conclusion: Vancomycin, Colistin, Ceftazidim, Imipenem, Amikacin, and Gentamycin had the highest drug sensitivity; while Cefotaxime, Clindamycin, and Chloramphenicol antibiotics had a low sensitivity. From 2014 to 2019, resistance to Colistin dramatically decreased.

Cites

No record.

References

Cite

APA: Copy

HASSANZAD, MARYAM, Sadati, Elham, GHORBANI, FARIBA, GHAFARIPOOR, HOSSEINALI, Farnia, Poopak, POORABDOLLAH, MIHAN, BAGHAEI, NOUSHIN, EMAMI, HABIB, & VELAYATI, ALI AKBAR. (2020). Evaluation of Antibiotic Resistance Trend among Cystic Fibrosis Patients: A Single Center Study from 2014-2019. INTERNATIONAL JOURNAL OF PEDIATRICS, 8(1 (73)), 10719-10729. SID. https://sid.ir/paper/777811/en

Vancouver: Copy

HASSANZAD MARYAM, Sadati Elham, GHORBANI FARIBA, GHAFARIPOOR HOSSEINALI, Farnia Poopak, POORABDOLLAH MIHAN, BAGHAEI NOUSHIN, EMAMI HABIB, VELAYATI ALI AKBAR. Evaluation of Antibiotic Resistance Trend among Cystic Fibrosis Patients: A Single Center Study from 2014-2019. INTERNATIONAL JOURNAL OF PEDIATRICS[Internet]. 2020;8(1 (73)):10719-10729. Available from: https://sid.ir/paper/777811/en

IEEE: Copy

MARYAM HASSANZAD, Elham Sadati, FARIBA GHORBANI, HOSSEINALI GHAFARIPOOR, Poopak Farnia, MIHAN POORABDOLLAH, NOUSHIN BAGHAEI, HABIB EMAMI, and ALI AKBAR VELAYATI, “Evaluation of Antibiotic Resistance Trend among Cystic Fibrosis Patients: A Single Center Study from 2014-2019,” INTERNATIONAL JOURNAL OF PEDIATRICS, vol. 8, no. 1 (73), pp. 10719–10729, 2020, [Online]. Available: https://sid.ir/paper/777811/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops