THE EFFECT OF SCROPHULARIA STRIATA EXTRACTS ON WOUND HEALING OF MICE

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JAFARY A.A.; LATIFI A.M.; SHOHRATI M.; HAJI HOSSEINI R.; SALESI M.

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Journal: Armaghane Danesh Year:2013 | Volume:18 | Issue:3 (75) Page(s): 194-209

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Title

THE EFFECT OF SCROPHULARIA STRIATA EXTRACTS ON WOUND HEALING OF MICE

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Keywords

SCROPHULARIA STRIATAQ1

HEALINGQ2

EXTRACTQ2

MICEQ2

Abstract

Background & aim: SCROPHULARIA STRIATA EXTRACT has been traditionally used for wound HEALING. The aim of this study was to evaluate the effect of SCROPHULARIA STRIATA EXTRACT on wound HEALING on MICE.Methods: In this experimental study, a number of 35 male MICE (NMRI) weighing 25-30 g were divided into 5 equal groups. Two 6 mm circular wounds were punched on the back of the MICE; moreover they were treated for 3 weeks in separate cages. The first group wasconsidered as the control group and the other groups were treated with phenytoin ointment 1%, alcoholic EXTRACT, hydroalcoholic and aqueous 10% twice a day for 21 days respectively. The wounds were daily photographed by a digital camera and the wound area was calculated using Image J software. Data were analysed by Kruskal- Wallis and Mann-Whitney test.Results: The average HEALING duration in the control group, phenytoin and EXTRACTs, aqueous and alcoholic were 9.1±3 6, 6.6±1.9, 6.5±1.7, 6.7±1.8 and 6.1±0.9 days respectively. The remaining scar size in these groups were 9.08±1.83, 5.84±1.20, 3.7±0.62, 3.5±0.74 and 2.81±0.79 millimeters respectively. The average duration of scar HEALING and the remaining treatment groups were significantly different from controls (p<0.05).Conclusion: SCROPHULARIA STRIATA EXTRACT decreased the period of wound HEALING in MICE. Among the three types of EXTRACTs, the hydroalcoholic EXTRACT demonstrated the best result.

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APA: Copy

JAFARY, A.A., LATIFI, A.M., SHOHRATI, M., HAJI HOSSEINI, R., & SALESI, M.. (2013). THE EFFECT OF SCROPHULARIA STRIATA EXTRACTS ON WOUND HEALING OF MICE. ARMAGHAN DANESH, 18(3 (75)), 194-209. SID. https://sid.ir/paper/77860/en

Vancouver: Copy

JAFARY A.A., LATIFI A.M., SHOHRATI M., HAJI HOSSEINI R., SALESI M.. THE EFFECT OF SCROPHULARIA STRIATA EXTRACTS ON WOUND HEALING OF MICE. ARMAGHAN DANESH[Internet]. 2013;18(3 (75)):194-209. Available from: https://sid.ir/paper/77860/en

IEEE: Copy

A.A. JAFARY, A.M. LATIFI, M. SHOHRATI, R. HAJI HOSSEINI, and M. SALESI, “THE EFFECT OF SCROPHULARIA STRIATA EXTRACTS ON WOUND HEALING OF MICE,” ARMAGHAN DANESH, vol. 18, no. 3 (75), pp. 194–209, 2013, [Online]. Available: https://sid.ir/paper/77860/en

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