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Information Journal Paper

Title

Effect of Foeniculum vulgare on Primary Dysmenorrhea: A Systematic Review and Meta-Analysis

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  0-0

Abstract

 Context: Dysmenorrhea is a common problem in Women. Objectives: This study aimed to summarize the results of all relevant clinical trials to draw a conclusion regarding the effect of Foeniculum vulgare on Primary Dysmenorrhea (PD). Methods: In this study, we searched 19 databases (including Medline/PubMed, Scopus, ISIWeb of Science) for the effects of Foeniculum vulgare on Primary Dysmenorrhea up to November 2016. The reference lists of the reviews and related articles were consulted to identify eligible articles. Studies investigating combinations of fennel and other products, without a control group, addressing premenstrual syndrome (PMS) and bleeding as the primary outcomes, and not being a randomized clinical trial (RCT) were excluded. A Meta-Analysis was performed to obtain a pooled estimate of effectiveness. The methodological quality was assessed using the modified Jadad scale. The registration number of this study is 95-01-65-11733. Results: Our search identified nine relevant articles for inclusion. The Meta-Analysis showed favorable effects of Foeniculum vulgare on Primary Dysmenorrhea for fixed effect (n = 727, OR = 0. 573, 95% CI: 0. 414 to 0. 793, P = 0. 001) and random effect (n = 727, OR = 0. 141, 95% CI: 0. 027 to 0. 742, P = 0. 021). The analysis also revealed a remarked heterogeneity (Q value = 198. 318, P = 0. 000, I2 = 95. 96,  2 = 6. 065). Conclusions: We found that the fennel extract is effective for Primary Dysmenorrhea. However, due to the heterogeneity of various findings, wewere unable tofindthe effective dosageandconcentration of this herbal medicine. Werecommendmulticenter clinical trials worldwide for evaluating the effectiveness of fennel in Primary Dysmenorrhea.

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    APA: Copy

    SALEHI, ALIREZA, MARZBAN, MARYAM, & AMINI, FATEMEH. (2019). Effect of Foeniculum vulgare on Primary Dysmenorrhea: A Systematic Review and Meta-Analysis. WOMENS HEALTH BULLETIN, 6(1), 0-0. SID. https://sid.ir/paper/779624/en

    Vancouver: Copy

    SALEHI ALIREZA, MARZBAN MARYAM, AMINI FATEMEH. Effect of Foeniculum vulgare on Primary Dysmenorrhea: A Systematic Review and Meta-Analysis. WOMENS HEALTH BULLETIN[Internet]. 2019;6(1):0-0. Available from: https://sid.ir/paper/779624/en

    IEEE: Copy

    ALIREZA SALEHI, MARYAM MARZBAN, and FATEMEH AMINI, “Effect of Foeniculum vulgare on Primary Dysmenorrhea: A Systematic Review and Meta-Analysis,” WOMENS HEALTH BULLETIN, vol. 6, no. 1, pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/779624/en

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