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Title

Factors Related to Mortality in Patients with Fournier’ s Gangrene or Necrotising Fasciitis; a 10-year Cross-Sectional Study

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Abstract

 Introduction: Fournier’; s Gangrene (FG) is a life-threatening disease, even with early diagnosis and administration of vigorous treatment, its Mortality rate is high. This study aimed to evaluate the factors relate to Mortality in patients with FG or necrotising fasciitis managed in a referral center. Methods: This retrospective crosssectional study was conducted on patients managed in a tertiary referral center, Tehran, Iran, from March 2009 toMarch 2019, with diagnosis of FG or necrotising fasciitis. The correlation between different demographic and clinical parameters with Mortality was analysed and reported. Results: 73 cases with the mean age of 59. 1 ± 15. 8 (range: 25 – 88) years were studied (87. 7% male). 21 (28. 8%) patients died. Escherichia coli (26 cases, 35. 6%) was the most frequent microorganism in cultures. Non-survived cases had higher mean age (p = 0. 01), higher frequency of hyperlipidaemia (p = 0. 02), immunosuppression (p < 0. 001), longer hospital stay (p=0. 02), lower blood pressure (p=0. 01), and lower platelet count (p=<0. 001). Based on multivariate analysis, age (p = 0. 015; Odds: 0. 88 (0. 79-0. 97)), haematocrit level (p = 0. 01; Odds: 1. 27 (1. 04-1. 55)), platelet count (p = 0. 03; Odds: 10. 11 (1. 14-89. 35)), and immunosuppression (p = 0. 01; Odds: 0. 01 (0. 0-0. 54))were independent related factors of Mortality. Conclusion: The rate of Mortality due to FG and necrotizing fasciitis was 28. 8%. Based on multivariate analysis, the independent related factors of Mortality were older age, lower haematocrit level and platelet count, and presence of immunosuppression.

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    APA: Copy

    Ansari Djafari, Anahita, RAHAVIAN, AMIRHOSSEIN, JAVANMARD, BABAK, Montazeri, Saeed, Shahabi, Vahid, HOJJATI, SEYYED ALI, Ghiasy, Saleh, Hamidi, Ramin, & KHOSHNEVIS, JALALUDDIN. (2021). Factors Related to Mortality in Patients with Fournier’ s Gangrene or Necrotising Fasciitis; a 10-year Cross-Sectional Study. ARCHIVES OF ACADEMIC EMERGENCY MEDICINE (EMERGENCY), 9(1), 0-0. SID. https://sid.ir/paper/780175/en

    Vancouver: Copy

    Ansari Djafari Anahita, RAHAVIAN AMIRHOSSEIN, JAVANMARD BABAK, Montazeri Saeed, Shahabi Vahid, HOJJATI SEYYED ALI, Ghiasy Saleh, Hamidi Ramin, KHOSHNEVIS JALALUDDIN. Factors Related to Mortality in Patients with Fournier’ s Gangrene or Necrotising Fasciitis; a 10-year Cross-Sectional Study. ARCHIVES OF ACADEMIC EMERGENCY MEDICINE (EMERGENCY)[Internet]. 2021;9(1):0-0. Available from: https://sid.ir/paper/780175/en

    IEEE: Copy

    Anahita Ansari Djafari, AMIRHOSSEIN RAHAVIAN, BABAK JAVANMARD, Saeed Montazeri, Vahid Shahabi, SEYYED ALI HOJJATI, Saleh Ghiasy, Ramin Hamidi, and JALALUDDIN KHOSHNEVIS, “Factors Related to Mortality in Patients with Fournier’ s Gangrene or Necrotising Fasciitis; a 10-year Cross-Sectional Study,” ARCHIVES OF ACADEMIC EMERGENCY MEDICINE (EMERGENCY), vol. 9, no. 1, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/780175/en

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