THE EFFECT OF HYDROALCOHOLIC EXTRACT OF MENTHA PIPERITA (COMPLEMENT TREATMENT) ON SEVERITY OF DEPRESSED PATIENTS

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NAJAFI DOULATABAD SH.; HASHEMI S.N.; MOHEBI NOUBANDEGANI Z.; SADEGHI HEYBAT ELAH; JAFARI AZIZ ELAH; NAJAFI DOULATABAD A.; ZOU ALADL M.

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Journal: Armaghane Danesh Year:2009 | Volume:14 | Issue:3 (55) Page(s): 83-90

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Title

THE EFFECT OF HYDROALCOHOLIC EXTRACT OF MENTHA PIPERITA (COMPLEMENT TREATMENT) ON SEVERITY OF DEPRESSED PATIENTS

Author(s)

Keywords

DEPRESSIONQ2

MENTHA PIPERITAQ3

TREATMENTQ3

Abstract

Introduction & Objective: DEPRESSION is a prevalent psychiatrical disease and among the most disabling psychiatrical health problems in various societies. It has been estimated that, till the year 2020, DEPRESSION will be the second prevalent disease after cardio-vascular disease and will include 15% of the human diseases. This study was carried out to determine the effect of hydroalcoholic extract of MENTHA PIPERITA (complement TREATMENT) on patient's DEPRESSION severity.Materials and Methods: This is a triple blind random clinical trial research carried out on depressed patients referred to the Shahid Mofateh Clinic of Yasouj city during 2007-2008. The patient's DEPRESSION severity was evaluated by Beck questionnaire and they were divided into 5 groups as random allocation and each group consisted of 24 persons. Then, Hydroalcoholic extract of MENTHA PIPERITA was given to four groups at the rate of 10.0mg, 50.0mg, 100.0mg and 200.0mg respectively per day and the fifth group received placebo. The TREATMENT was continued for a period of two months. After this period, again the DEPRESSION rates of patients were evaluated with the help of same questionnaire and were compared with the rates before the intervention. Collected data were analyzed with the help of descriptive tests, x2 statistical tests, one way variance analyzed and variance with repeated measurements.Results: The results of the study indicated that the highest anti DEPRESSION effect was seen in those patients who received 100.0mg and 200.0mg of the extract and the lowest rate allocated to the groups of 50.0mg, placebo group and 10.0mg respectively.Statistical analysis using repeated measurements confirmed the difference at the level of 0.1 between the mean of DEPRESSION rate of the five research groups before and after intervention (p=0.078).Conclusion: Based on the results of the current study, spearmint juice at the rate of 100.0mg and 200.0mg can be used as supplement in TREATMENT of depressed patients. However, more studies are needed to find out the proper dose of the extract.

Cites

STUDY THE EFFECT OF INHALATION OF PEPPERMINT OIL ON DEPRESSION AND ANXIETY IN PATIENTS WITH MYOCARDIAL INFARCTION WHO ARE HOSPITALIZED IN INTENSIVE CARE UNITS OF SIRJAN

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APA: Copy

NAJAFI DOULATABAD, SH., HASHEMI, S.N., MOHEBI NOUBANDEGANI, Z., SADEGHI, HEYBAT ELAH, JAFARI, AZIZ ELAH, NAJAFI DOULATABAD, A., & ZOU ALADL, M.. (2009). THE EFFECT OF HYDROALCOHOLIC EXTRACT OF MENTHA PIPERITA (COMPLEMENT TREATMENT) ON SEVERITY OF DEPRESSED PATIENTS. ARMAGHAN DANESH, 14(3 (55)), 83-90. SID. https://sid.ir/paper/78032/en

Vancouver: Copy

NAJAFI DOULATABAD SH., HASHEMI S.N., MOHEBI NOUBANDEGANI Z., SADEGHI HEYBAT ELAH, JAFARI AZIZ ELAH, NAJAFI DOULATABAD A., ZOU ALADL M.. THE EFFECT OF HYDROALCOHOLIC EXTRACT OF MENTHA PIPERITA (COMPLEMENT TREATMENT) ON SEVERITY OF DEPRESSED PATIENTS. ARMAGHAN DANESH[Internet]. 2009;14(3 (55)):83-90. Available from: https://sid.ir/paper/78032/en

IEEE: Copy

SH. NAJAFI DOULATABAD, S.N. HASHEMI, Z. MOHEBI NOUBANDEGANI, HEYBAT ELAH SADEGHI, AZIZ ELAH JAFARI, A. NAJAFI DOULATABAD, and M. ZOU ALADL, “THE EFFECT OF HYDROALCOHOLIC EXTRACT OF MENTHA PIPERITA (COMPLEMENT TREATMENT) ON SEVERITY OF DEPRESSED PATIENTS,” ARMAGHAN DANESH, vol. 14, no. 3 (55), pp. 83–90, 2009, [Online]. Available: https://sid.ir/paper/78032/en

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