Platelet Microparticle Controversial Role in Cancer (Review Article)

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NAZARI MAHNAZ; Javandoost Ehsan; TALEBI MEHDI; MOVASSAGHPOUR ALIAKBAR; SOLEIMANI MASOUD

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Journal: Advanced Pharmaceutical Bulletin Year:2021 | Volume:11 | Issue:1 Page(s): 39-55

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Title

Platelet Microparticle Controversial Role in Cancer (Review Article)

Author(s)

Keywords

PMP

platelet

microparticle

cancer

Abstract

platelet-derived microparticles (PMPs) are a group of micrometer-scale extracellular vesicles released by platelets upon activation that are responsible for the majority of microvesicles found in plasma. PMPs’ physiological properties and functions have long been investigated by researchers. In this regard, a noticeable area of studies has been devoted to evaluating the potential roles and effects of PMPs on cancer progression. Clinical and experimental evidence conflictingly implicates supportive and suppressive functions for PMPs regarding cancer. Many of these functions could be deemed as a cornerstone for future considerations of PMPs usage in cancer targeted therapy. This review discusses what is currently known about PMPs and provides insights for new and possible research directions for further grasping the intricate interplay between PMPs and cancer.

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APA: Copy

NAZARI, MAHNAZ, Javandoost, Ehsan, TALEBI, MEHDI, MOVASSAGHPOUR, ALIAKBAR, & SOLEIMANI, MASOUD. (2021). Platelet Microparticle Controversial Role in Cancer (Review Article). ADVANCED PHARMACEUTICAL BULLETIN, 11(1), 39-55. SID. https://sid.ir/paper/780372/en

Vancouver: Copy

NAZARI MAHNAZ, Javandoost Ehsan, TALEBI MEHDI, MOVASSAGHPOUR ALIAKBAR, SOLEIMANI MASOUD. Platelet Microparticle Controversial Role in Cancer (Review Article). ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2021;11(1):39-55. Available from: https://sid.ir/paper/780372/en

IEEE: Copy

MAHNAZ NAZARI, Ehsan Javandoost, MEHDI TALEBI, ALIAKBAR MOVASSAGHPOUR, and MASOUD SOLEIMANI, “Platelet Microparticle Controversial Role in Cancer (Review Article),” ADVANCED PHARMACEUTICAL BULLETIN, vol. 11, no. 1, pp. 39–55, 2021, [Online]. Available: https://sid.ir/paper/780372/en

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