INVESTIGATION OF INTERLEUKIN -18 GENE POLYMORPHISMS AND SERUM LEVEL IN PATIENTS WITH PREECLAMPSIA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SOLIMANIPOUR M.; NAEIMI S.; ERFANI N.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Armaghane Danesh Year:2011 | Volume:16 | Issue:4 (64) Page(s): 362-371

Download Full-Text

Persian Verion

View:

734

Download:

Cites:

Information Journal Paper

Title

INVESTIGATION OF INTERLEUKIN -18 GENE POLYMORPHISMS AND SERUM LEVEL IN PATIENTS WITH PREECLAMPSIA

Author(s)

SOLIMANIPOUR M. | NAEIMI S. | ERFANI N. | Issue Writer Certificate

Keywords

IL-18Q2

POLYMORPHISMQ3

PREECLAMPSIAQ2

GENOTYPEQ2

Abstract

Background & Aim: PREECLAMPSIA is one of the most important factors in fetal and maternal mortality that seems to change immunological parameters such as rate of auto antibodies and cytokines involved in the disease. This study aimed to evaluate the serum level and frequency of the two POLYMORPHISMs in the IL-18 gene promoter in patients with PREECLAMPSIA and normal pregnant women.Methods: In the present case-control study conducted at Islamic Azad University of Estahban in 2009-2010, fifty PREECLAMPSIA patients and 103 healthy pregnant women were enrolled. Single nucleotide POLYMORPHISMs of the IL-18 gene at positions -607 (C/A) and -137 (G/C) were analyzed by the Allel specific PCR method. IL-18 serum level was determined, using ELISA method. Data were analyzed with chi-square tests, Mann-Whitney and the Hardy Weinberg equilibrium.Results: No significant association was found between the serum level, allele, GENOTYPE, and haplotype distributions of the SNPs and PREECLAMPSIA (p>0.05).Conclusion: Results of this study showed that IL-18 gene promoter POLYMORPHISMs at positions -607 and -137 and serum level did not confer susceptibility to PREECLAMPSIA in patients.

Cites

No record.

References

No record.

Cite

APA: Copy

SOLIMANIPOUR, M., NAEIMI, S., & ERFANI, N.. (2011). INVESTIGATION OF INTERLEUKIN -18 GENE POLYMORPHISMS AND SERUM LEVEL IN PATIENTS WITH PREECLAMPSIA. ARMAGHAN DANESH, 16(4 (64)), 362-371. SID. https://sid.ir/paper/78042/en

Vancouver: Copy

SOLIMANIPOUR M., NAEIMI S., ERFANI N.. INVESTIGATION OF INTERLEUKIN -18 GENE POLYMORPHISMS AND SERUM LEVEL IN PATIENTS WITH PREECLAMPSIA. ARMAGHAN DANESH[Internet]. 2011;16(4 (64)):362-371. Available from: https://sid.ir/paper/78042/en

IEEE: Copy

M. SOLIMANIPOUR, S. NAEIMI, and N. ERFANI, “INVESTIGATION OF INTERLEUKIN -18 GENE POLYMORPHISMS AND SERUM LEVEL IN PATIENTS WITH PREECLAMPSIA,” ARMAGHAN DANESH, vol. 16, no. 4 (64), pp. 362–371, 2011, [Online]. Available: https://sid.ir/paper/78042/en

Related Journal Papers