Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

179
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

92
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Platelet and Haemostasis are the Main Targets in Severe Cases of COVID-19 Infection; a System Biology Study

Pages

  0-0

Abstract

 Introduction: Many proteomics-based and Bioinformatics-based efforts are made to detect the molecular mechanism of COVID-19 infection. Identification of the main protein targets and pathways of severe cases of COVID-19 infection is the aim of this study. Methods: Published differentially expressed Proteins were screened and the significant Proteins were investigated via protein-protein interaction network using Cytoscape software V. 3. 7. 2 and STRING database. The studied Proteins were assessed via action map analysis to determine the relationship between individual Proteins using CluePedia. The related biological terms were investigated using ClueGO and the terms were clustered and discussed. Results: Among the 35 queried Proteins, six of them (FGA, FGB, FGG, and FGl1 plus TLN1 and THBS1) were identified as critical Proteins. A total of 38 biological terms, clustered in 4 groups, were introduced as the affected terms. “ Platelet degranulation” and “ hereditary factor I deficiency disease” were introduced as the main class of the terms disturbed by COVID-19 virus. Conclusion: It can be concluded that platelet damage and disturbed haemostasis could be the main targets in severe cases of coronavirus infection. It is vital to follow patients’ condition by examining the introduced critical differentially expressed Proteins (DEPs).

Cites

  • No record.

    • References

    Cite

    APA: Copy

    ZAMANIAN AZODI, MONA, ARJMAND, BABAK, RAZZAGHI, MOHAMMADREZA, REZAEI TAVIRANI, MOSTAFA, AHMADZADEH, ALIREZA, & RostamiNejad, Mohammad. (2021). Platelet and Haemostasis are the Main Targets in Severe Cases of COVID-19 Infection; a System Biology Study. ARCHIVES OF ACADEMIC EMERGENCY MEDICINE (EMERGENCY), 9(1), 0-0. SID. https://sid.ir/paper/783108/en

    Vancouver: Copy

    ZAMANIAN AZODI MONA, ARJMAND BABAK, RAZZAGHI MOHAMMADREZA, REZAEI TAVIRANI MOSTAFA, AHMADZADEH ALIREZA, RostamiNejad Mohammad. Platelet and Haemostasis are the Main Targets in Severe Cases of COVID-19 Infection; a System Biology Study. ARCHIVES OF ACADEMIC EMERGENCY MEDICINE (EMERGENCY)[Internet]. 2021;9(1):0-0. Available from: https://sid.ir/paper/783108/en

    IEEE: Copy

    MONA ZAMANIAN AZODI, BABAK ARJMAND, MOHAMMADREZA RAZZAGHI, MOSTAFA REZAEI TAVIRANI, ALIREZA AHMADZADEH, and Mohammad RostamiNejad, “Platelet and Haemostasis are the Main Targets in Severe Cases of COVID-19 Infection; a System Biology Study,” ARCHIVES OF ACADEMIC EMERGENCY MEDICINE (EMERGENCY), vol. 9, no. 1, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/783108/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top