INTRODUCTION OF A NEW INDEX TO COMPARE FUNCTION OF SCREENING LABS OF THALASSEMIA PREVENTION PROGRAM IN ISFAHAN PROVINCE

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ZEYNALIAN M.; MOAFI A.R.; FADAEI NOUBARI R.; HEYDARI KAMAL

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Journal: The Scientific Journal of Iranian Blood Transfusion Year:2009 | Volume:6 | Issue:2 (23) Page(s): 131-139

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Title

INTRODUCTION OF A NEW INDEX TO COMPARE FUNCTION OF SCREENING LABS OF THALASSEMIA PREVENTION PROGRAM IN ISFAHAN PROVINCE

Author(s)

ZEYNALIAN M. | MOAFI A.R. | FADAEI NOUBARI R. | HEYDARI KAMAL | Issue Writer Certificate

Keywords

THALASSEMIAQ3

SCREENINGQ2

IRANQ3

Abstract

Background and Objectives: Although major beta-THALASSEMIA prevention and control program is one of the most successful programs in genetics field, there are new cases of major beta-THALASSEMIA due to laboratory errors. So the laboratory quality control (QC) is very important to diagnose carriers in preventive programs. At present, there is not a distinct and measurable index for function assessment and comparison in SCREENING laboratories; this urged us to create an objective, measurable and explicit index for health care givers. For this purpose, we compared the function of SCREENING labs in districts of Isfahan Province.Materials and Methods: In this cross-sectional study, we collected the data from "pre-marriage SCREENING program" in 18 districts (19 SCREENING labs) covered by Isfahan University of Medical Sciences from 2006 to 2008. The percentage rates of "screened males with low blood indexes" in every 3 months (P index) were assessed; then, the average and coefficient variants in duration of 3 years were calculated with excel software. Based on these findings, "screening labs’ functions" were assessed and compared.Results: The least "CVs of P index" within 19 labs was found to be in Mobarakeh laboratory (10.4%) and Provincial reference lab (10.9%), respectively. The highest CVs were found in Khour (76.3%) and Tiran and Karvan labs (58.2%), respectively. The P index average in all centers was 14% (13.9% in reference lab) with the highest being in Mobarakeh (24.2%) and the lowest in Khour (8.8%).Conclusions: Whereas the number of marriage candidates in each SCREENING lab is relatively stable, the centers with the highest CV value of P index are probably lower in function level as compared with the centers with the lowest CV value of P index (as in reference SCREENING lab). CV of P index may be a good evidence for quality of "screening lab function" and should be evaluated annually. The SCREENING labs with high CV of P index need more attention and evaluation.

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APA: Copy

ZEYNALIAN, M., MOAFI, A.R., FADAEI NOUBARI, R., & HEYDARI, KAMAL. (2009). INTRODUCTION OF A NEW INDEX TO COMPARE FUNCTION OF SCREENING LABS OF THALASSEMIA PREVENTION PROGRAM IN ISFAHAN PROVINCE. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 6(2 (23)), 131-139. SID. https://sid.ir/paper/78344/en

Vancouver: Copy

ZEYNALIAN M., MOAFI A.R., FADAEI NOUBARI R., HEYDARI KAMAL. INTRODUCTION OF A NEW INDEX TO COMPARE FUNCTION OF SCREENING LABS OF THALASSEMIA PREVENTION PROGRAM IN ISFAHAN PROVINCE. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2009;6(2 (23)):131-139. Available from: https://sid.ir/paper/78344/en

IEEE: Copy

M. ZEYNALIAN, A.R. MOAFI, R. FADAEI NOUBARI, and KAMAL HEYDARI, “INTRODUCTION OF A NEW INDEX TO COMPARE FUNCTION OF SCREENING LABS OF THALASSEMIA PREVENTION PROGRAM IN ISFAHAN PROVINCE,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 6, no. 2 (23), pp. 131–139, 2009, [Online]. Available: https://sid.ir/paper/78344/en

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