PREVALENCE OF ALLOIMMUNIZATION AGAINST RBC ANTIGENS IN THALASSEMIA MAJOR PATIENTS OF LORESTAN PROVINCE IN 1383

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KIANI A.; SHIRKHANI Y.; KASHI M.; ABDI JAHANGIR

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON) Year:2006 | Volume:3 | Issue:3 Page(s): 265-271

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

4,548

Download:

Cites:

Information Journal Paper

Title

PREVALENCE OF ALLOIMMUNIZATION AGAINST RBC ANTIGENS IN THALASSEMIA MAJOR PATIENTS OF LORESTAN PROVINCE IN 1383

Author(s)

KIANI A. | SHIRKHANI Y. | KASHI M. | ABDI JAHANGIR | Issue Writer Certificate

Keywords

ALLOIMMUNIZATIONQ4

PANELQ4

THALASSEMIA MAJORQ3

Abstract

Background and Objectives: THALASSEMIA MAJOR patients should continuously receive blood to survive. Permanent blood injection will expose patients' immune system to a broad spectrum of new antigens located on the surface of injected RBCs. Continuous exposure to foreign antigens may provoke antibody production against them in the patients who lack those Ags. This phenomenon is termed ALLOIMMUNIZATION and can cause problems for preparation of compatible blood for transfusion. Materials and Methods: 65 patients were studied in this research. At first, questionnaires eliciting information about age, race, date of blood injection, splenectomy, presence of any underlying diseases, and any certain drugs (in patients' records) were filled out by all patients. For alloantibody screening, patients' serum samples were tested by the PANELs prepared in IBTO. Phenotypes of RBCs for Ags of ABH and Rh (D, C, E, c, e) were also determined by relevant antisera. Results: Out of 65 patients, only one case (1.53%) had been allommunized. The age range of males and females were 13 ± 6 and 13 ± 5 respectively. All of the patients were of Lurish race. The first blood transfusion in all of them occurred at the age below 3. Seventeen subjects were splenectomized. Conclusions: The reasons for low prevalence of ALLOIMMUNIZATION against RBCs in THALASSEMIA MAJOR patients may pertain to similarity of patients and donors by descent, blood transfusion before the age 3, and splenectomy in a few patients. Identification of alloantibodies by using the PANEL cells was the best method to provide patients with antigen negative and compatible blood for transfusion.

Cites

SCREENING AND IDENTIFYING OF ERYTHROCYTE ALLOANTIBODIES IN PATIENTS WITH THALASSEMIA MAJOR REFERRED TO AHVAZ SHAFA HOSPITAL

References

EVALUATION OF ALLOIMMUNIZATION IN MAJOR B. THALASSEMIC PATIENTS IN ZAHEDAN IN 2001

Cite

APA: Copy

KIANI, A., SHIRKHANI, Y., KASHI, M., & ABDI, JAHANGIR. (2006). PREVALENCE OF ALLOIMMUNIZATION AGAINST RBC ANTIGENS IN THALASSEMIA MAJOR PATIENTS OF LORESTAN PROVINCE IN 1383. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 3(3), 265-271. SID. https://sid.ir/paper/78361/en

Vancouver: Copy

KIANI A., SHIRKHANI Y., KASHI M., ABDI JAHANGIR. PREVALENCE OF ALLOIMMUNIZATION AGAINST RBC ANTIGENS IN THALASSEMIA MAJOR PATIENTS OF LORESTAN PROVINCE IN 1383. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2006;3(3):265-271. Available from: https://sid.ir/paper/78361/en

IEEE: Copy

A. KIANI, Y. SHIRKHANI, M. KASHI, and JAHANGIR ABDI, “PREVALENCE OF ALLOIMMUNIZATION AGAINST RBC ANTIGENS IN THALASSEMIA MAJOR PATIENTS OF LORESTAN PROVINCE IN 1383,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 3, no. 3, pp. 265–271, 2006, [Online]. Available: https://sid.ir/paper/78361/en

Related Journal Papers