THE RESULTS OF TWO METHODS OF FACTOR VIII: C IN PATIENTS WITH HEMOPHILIA A VOSOUGH

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VOSOUGH SHIRAYEH F.; AHMADINEJAD M.; TOOGEH GH.; KARIMI K.; TABATABAEI M.R.; HOMAYOUN S.

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Journal: THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON) Year:2017 | Volume:13 | Issue:4 Page(s): 277-283

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Title

THE RESULTS OF TWO METHODS OF FACTOR VIII: C IN PATIENTS WITH HEMOPHILIA A VOSOUGH

Author(s)

Keywords

HEMOPHILIA AQ2

FACTOR VIIIQ3

PREVALENCEQ4

Abstract

Background and Objectives FVIII activity (FVIII: C) is measured by clotting or chromogenic methods. The results of these methods may be different in some cases of HEMOPHILIA A that can cause misdiagnosis. The Aim of this study is to assess the results of two methods of F VIII: C assay in patients with HEMOPHILIA A Materials and Methods In A descriptive survey research, FVIII: C level was measured using one-stage and chromogenic assays in 73 HEMOPHILIA A known patients. The data were analyzed by t-test and SPSS 22 statistical method.Results From 73 patients in this study, the range of FVIII: C assay by one-stage method was 4% to 81% (mean=22.7, SD=14.8) and the range of FVIII: C assay by chromogenic method was 1% to 123 % (mean=16.5, SD=21).Conclusions For prevention of misdiagnosis, it is recommended to use two methods of FVIII: C assays for diagnosis of patients with HEMOPHILIA A.

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References

CLINICAL AND LABORATORY APPROACHES TO HEMOPHILIA A

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APA: Copy

VOSOUGH SHIRAYEH, F., AHMADINEJAD, M., TOOGEH, GH., KARIMI, K., TABATABAEI, M.R., & HOMAYOUN, S.. (2017). THE RESULTS OF TWO METHODS OF FACTOR VIII: C IN PATIENTS WITH HEMOPHILIA A VOSOUGH. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 13(4), 277-283. SID. https://sid.ir/paper/78366/en

Vancouver: Copy

VOSOUGH SHIRAYEH F., AHMADINEJAD M., TOOGEH GH., KARIMI K., TABATABAEI M.R., HOMAYOUN S.. THE RESULTS OF TWO METHODS OF FACTOR VIII: C IN PATIENTS WITH HEMOPHILIA A VOSOUGH. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2017;13(4):277-283. Available from: https://sid.ir/paper/78366/en

IEEE: Copy

F. VOSOUGH SHIRAYEH, M. AHMADINEJAD, GH. TOOGEH, K. KARIMI, M.R. TABATABAEI, and S. HOMAYOUN, “THE RESULTS OF TWO METHODS OF FACTOR VIII: C IN PATIENTS WITH HEMOPHILIA A VOSOUGH,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 13, no. 4, pp. 277–283, 2017, [Online]. Available: https://sid.ir/paper/78366/en

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