Evaluating the serum zinc and vitamin D levels in alopecia areata

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SANIEE SARA; GHAREAGHAJI ZARE ARMAGHAN; Radmehr Afsaneh

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Journal Paper

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Journal: Iranian Journal of Dermatology Year:2018 | Volume:21 | Issue:3 Page(s): 77-80

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Title

Evaluating the serum zinc and vitamin D levels in alopecia areata

Author(s)

SANIEE SARA | GHAREAGHAJI ZARE ARMAGHAN | Radmehr Afsaneh | Issue Writer Certificate

Keywords

alopecia areata

vitamin D

zinc

Abstract

Background: alopecia areata (AA) is a common localized nonscarring hair loss. vitamin D and such trace elements as zinc have significant immunomodulatory roles and are reduced in many autoimmune diseases. We aim to evaluate the zinc and vitamin D levels in AA patients belonging to an Iranian population. Methods: We randomly recruited 77 patients with AA, and 112 age-and sex-matched normal subjects. Serum zinc and vitamin D levels were measured and compared between groups. Patients were considered vitamin D deficient or insufficient if 25-OH vitamin D levels were <10 and 10 to 30 ng/ml, respectively. Results: Disease duration was 6. 73± 1. 05 months. Compared to the control group, AA patients had significantly lower zinc (87. 78± 20. 61 vs. 92. 76± 28. 00, p=0. 008) and vitamin D levels (20. 23± 11. 11 vs. 25. 63± 15. 90, p=0. 01) and higher vitamin D deficiency (19. 5% vs. 10. 7%, p=0. 03). There were significant correlations between AA duration and zinc levels (r=0. 483, p<0. 001); no recognizable relationship, on the other hand, was observed with vitamin D levels (r=0. 022, p=0. 84). Conclusion: There were significantly lower levels of zinc and vitamin D in AA patients, compared to normal subjects. zinc level is inversely correlated with disease duration, and both zinc and vitamin D play crucial roles in AA pathogenesis and are possible supplements in AA treatment.

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APA: Copy

SANIEE, SARA, GHAREAGHAJI ZARE, ARMAGHAN, & Radmehr, Afsaneh. (2018). Evaluating the serum zinc and vitamin D levels in alopecia areata. IRANIAN JOURNAL OF DERMATOLOGY, 21(3), 77-80. SID. https://sid.ir/paper/785265/en

Vancouver: Copy

SANIEE SARA, GHAREAGHAJI ZARE ARMAGHAN, Radmehr Afsaneh. Evaluating the serum zinc and vitamin D levels in alopecia areata. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2018;21(3):77-80. Available from: https://sid.ir/paper/785265/en

IEEE: Copy

SARA SANIEE, ARMAGHAN GHAREAGHAJI ZARE, and Afsaneh Radmehr, “Evaluating the serum zinc and vitamin D levels in alopecia areata,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 21, no. 3, pp. 77–80, 2018, [Online]. Available: https://sid.ir/paper/785265/en

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