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Information Journal Paper

Title

A Systematic Review of Screening Tests for Chronic Kidney Disease: An Accuracy Analysis

Pages

  0-0

Abstract

 This Systematic Review was conducted to assess the diagnostic accuracy of Chronic Kidney Disease Screening tests in the general population. MEDLINE, EMBASE, Web of Science, Scopus, The Cochrane Library and ProQuest databases were searched for English-language publications up to November 2016. Two reviewers independently screened studies and extracted study data in standardized tables. Methodological quality was assessed using the QUADAS-2 tool. Sensitivity and Specificity of all available Screening methods were identified through included studies. Ten out of 1349 screened records included for final analysis. Sensitivities of the dipstick test with a cutoff value of trace were ranged from 37. 1% to 69. 4% and specificities from 93. 7% to 97. 3% for the detection of ACR>30 mg/g. The diagnostic sensitivities of the UAC>10 mg/dL testing was shown to vary from 40% to 87%, and specificities ranged from 75% to 96%. While the sensitivities of ACR were fluctuating between 74% and 90%, likewise the specificities were between 77% and 88%. Sensitivities for C-G, Grubb and Larsson equations were 98. 9%, 86. 2%, and 70. 1% respectively. In the meantime the study showed specificities of 84. 8%, 84. 2% and 90. 5% respectively for these equations. Individual studies were highly heterogeneous in terms of target populations, type of Screening tests, thresholds used to detect CKD and variations in design. Results pointed to the superiority of UAC and dipstick over the other tests in terms of all parameters involved. The diversity of methods and thresholds for detection of CKD, necessitate considering the cost parameter along with the effectiveness of tests to scale-up an efficient strategy.

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    APA: Copy

    Keshvari Shad, Fatemeh, HAJEBRAHIMI, SAKINEH, Pilar Laguna Pes, Maria, MAHBOUB AHARI, ALIREZA, NOURI, MOHAMMAD, SEYEDNEJAD, FARSHAD, & YOUSEFI, MAHMOOD. (2020). A Systematic Review of Screening Tests for Chronic Kidney Disease: An Accuracy Analysis. GALEN MEDICAL JOURNAL, 9(1), 0-0. SID. https://sid.ir/paper/786104/en

    Vancouver: Copy

    Keshvari Shad Fatemeh, HAJEBRAHIMI SAKINEH, Pilar Laguna Pes Maria, MAHBOUB AHARI ALIREZA, NOURI MOHAMMAD, SEYEDNEJAD FARSHAD, YOUSEFI MAHMOOD. A Systematic Review of Screening Tests for Chronic Kidney Disease: An Accuracy Analysis. GALEN MEDICAL JOURNAL[Internet]. 2020;9(1):0-0. Available from: https://sid.ir/paper/786104/en

    IEEE: Copy

    Fatemeh Keshvari Shad, SAKINEH HAJEBRAHIMI, Maria Pilar Laguna Pes, ALIREZA MAHBOUB AHARI, MOHAMMAD NOURI, FARSHAD SEYEDNEJAD, and MAHMOOD YOUSEFI, “A Systematic Review of Screening Tests for Chronic Kidney Disease: An Accuracy Analysis,” GALEN MEDICAL JOURNAL, vol. 9, no. 1, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/786104/en

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