THE EVALUATION OF CYTOMEGALOVIRUS IN INFANTS FOLLOWING EXCHANGE TRANSFUSION IN CHILDREN MEDICAL HOSPITAL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZANDIEH T.; KAVIANI SAEID; DERAKHSHAN M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: The Scientific Journal of Iranian Blood Transfusion Year:2005 | Volume:2 | Issue:4 Page(s): 83-89

Download Full-Text

Persian Verion

View:

819

Download:

Cites:

Information Journal Paper

Title

THE EVALUATION OF CYTOMEGALOVIRUS IN INFANTS FOLLOWING EXCHANGE TRANSFUSION IN CHILDREN MEDICAL HOSPITAL

Author(s)

ZANDIEH T. | KAVIANI SAEID | DERAKHSHAN M. | Issue Writer Certificate

Keywords

CYTOMEGALOVIRUSQ4

HYPERBILIRUBINEAMIAQ4

BLOOD TRANSFUSIONQ4

Abstract

Background and Objectives During the infancy period, exchange transfusion is the main and effective method of cure for hyperdilirubineamia in hemolytic neonates. One of the risks involved in these patients is CMV infection. Since CMV can inflict and kill children with immunodeficiency, we decided to evaluate blood transmitted CMV infection in infants for the first time in Iran. Materials and Methods ln this prospective study, the levels of lgG and IgM antibody against CMV in infants blood sera before and after exchange transfusion, sera of their mothers, and the plasma of donors were evaluated by ELISA method and conventional kits. The data were then analyzed by nonparametric and mac nemar test. Results The level of specific IgM antibody of CMV was 14% in the serum of infants before exchange transfusion and 48% two months after exchange which came out to be significant (p<0.0001). This indicates transmittability of CMV infection through BLOOD TRANSFUSION since the amount of primary infection of CMV in mothers (IgM) was only 1%. Conclusions According to the high level of CMV infection in infants (14%) compared to mothers (1%), it can be concluded that some mothers have latent CMV infection. On the other hand, the high level of CMV infection in infants (48%) 2 months after transfusion is cause of post-transfusion CMV infection. Analysis of the data obtained from dependent variables such as volume of transfused blood, number of exchange transfusion attempts, weight, age, sex and blood group analyzed by the nonparametric method indicated that the volume of transfused blood to infants has a direct correlation with the rate of transmission of infection to them but other variables do not have any correlation.

Cites

SEROEPIDEMIOLOGY OF HUMAN CYTOMEGALOVIRUS IN PREGNANT WOMEN AND THEIR NEONATES IN KERMAN CITY DURING 2005

References

No record.

Cite

APA: Copy

ZANDIEH, T., KAVIANI, SAEID, & DERAKHSHAN, M.. (2005). THE EVALUATION OF CYTOMEGALOVIRUS IN INFANTS FOLLOWING EXCHANGE TRANSFUSION IN CHILDREN MEDICAL HOSPITAL. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 2(4), 83-89. SID. https://sid.ir/paper/78720/en

Vancouver: Copy

ZANDIEH T., KAVIANI SAEID, DERAKHSHAN M.. THE EVALUATION OF CYTOMEGALOVIRUS IN INFANTS FOLLOWING EXCHANGE TRANSFUSION IN CHILDREN MEDICAL HOSPITAL. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2005;2(4):83-89. Available from: https://sid.ir/paper/78720/en

IEEE: Copy

T. ZANDIEH, SAEID KAVIANI, and M. DERAKHSHAN, “THE EVALUATION OF CYTOMEGALOVIRUS IN INFANTS FOLLOWING EXCHANGE TRANSFUSION IN CHILDREN MEDICAL HOSPITAL,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 2, no. 4, pp. 83–89, 2005, [Online]. Available: https://sid.ir/paper/78720/en

Related Journal Papers