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Information Journal Paper

Title

ANTIBIOTIC RESISTANCE OF SALMONELLA ENTERICA PRODUCING EXTENDED-SPECTRUM B-LACTAMASES (ESBLS) TYPE CMY-2, IN POULTRY

Pages

  109-115

Abstract

 Background and Objective: Salmonella is one of the most important zoonotic pathogens responsible for food-borne infections all over the world. Poultry products are widely acknowledged to be a significant reservoir for Salmonella. This study was done to evaluate the antibiotic resistant of SALMONELLA ENTERICA producer of beta lactamase spectrum in poultry.Methods: In this descriptive – laboratort study 70 SALMONELLA ENTERICA serotypes were collected from poultry. All Salmonella isolates were tested to antimicrobial susceptibility testing by the Kirby-Bauer disk diffusion according to Clinical Laboratory Standards Institute (CLSI). Twenty-nine antibiotics were used in this study.Klebsiella pneumoniae; ATCC 700603 was used as quality control strains. The isolates were determined to be ESBL-producing Salmonella by the conventional double-disk synergy and genotypic method.Results: Among 70 salmonella isolates, the most prevalent serotypes were S. typhimurium and S. enteritidis. All serotypes were susceptible to gentamicin, ciprofloxacin, oflaxacin, imipenem, enrofloxacin. The common resistance was observed to cephalexin (96%), cefazolin (96%) and cephalotin (65%). Among the 70Salmonella isolates studied, multi-drug resistance was observed in 59 (84%) isolates. Forty-seven (67%) isolates were found to be ESBL-producing isolates. PCR assay of all isolates showed that 17 isolates (33.3%) carried balaCMY2 gene.Conclusion: This study showed that antibiotic resistance to SALMONELLA ENTERICA serotypes is due to beta lactamase enzyme in this strain is considerably increased in poultry.

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    APA: Copy

    NADERI MOZAJIN, MARYAM, KHAKI, PEJVAK, & NOORBAKHSH, FATEMEH. (2018). ANTIBIOTIC RESISTANCE OF SALMONELLA ENTERICA PRODUCING EXTENDED-SPECTRUM B-LACTAMASES (ESBLS) TYPE CMY-2, IN POULTRY. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 20(2 (66) ), 109-115. SID. https://sid.ir/paper/79204/en

    Vancouver: Copy

    NADERI MOZAJIN MARYAM, KHAKI PEJVAK, NOORBAKHSH FATEMEH. ANTIBIOTIC RESISTANCE OF SALMONELLA ENTERICA PRODUCING EXTENDED-SPECTRUM B-LACTAMASES (ESBLS) TYPE CMY-2, IN POULTRY. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;20(2 (66) ):109-115. Available from: https://sid.ir/paper/79204/en

    IEEE: Copy

    MARYAM NADERI MOZAJIN, PEJVAK KHAKI, and FATEMEH NOORBAKHSH, “ANTIBIOTIC RESISTANCE OF SALMONELLA ENTERICA PRODUCING EXTENDED-SPECTRUM B-LACTAMASES (ESBLS) TYPE CMY-2, IN POULTRY,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 20, no. 2 (66) , pp. 109–115, 2018, [Online]. Available: https://sid.ir/paper/79204/en

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