ASSOCIATION OF APE1 GENE ASP148GLU POLYMORPHISM AND IDIOPATHIC MALE INFERTILITY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

YOUSEFI M.; SALEHI Z.; MASHAYEKHI F.; BAHADORI M.H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2015 | Volume:17 | Issue:2 (54) Page(s): 87-91

Download Full-Text

Persian Verion

View:

772

Download:

Cites:

Information Journal Paper

Title

ASSOCIATION OF APE1 GENE ASP148GLU POLYMORPHISM AND IDIOPATHIC MALE INFERTILITY

Author(s)

YOUSEFI M. | SALEHI Z. | MASHAYEKHI F. | BAHADORI M.H. | Issue Writer Certificate

Keywords

INFERTILITYQ2

MALEQ2

POLYMORPHISMQ2

APE1 GENEQ2

Abstract

Background and Objective: Despite enormous progress in the understanding of human reproductive physiology, the underlying cause of MALE INFERTILITY remains undefined in about 50.0% of cases, which are referred to as idiopathic INFERTILITY and affects about 5.0-7.0% of the general MALE population. Human apurinic/apyrimidinic endonuclease (ApE1) is a multifunctional protein that has an important role in the base excision repair (BER) pathway. ApE1 SNP T>G found in exon 5 led to substitution of Asp>Glu at codon 148. This study was done to evaluate the association of ApE1 Asp148Glu POLYMORPHISM and the risk of idiopathic MALE INFERTILITY.Methods: In this case-control study, blood samples were collected from 90 patients diagnosed with idiopathic MALE INFERTILITY and 90 healthy men, genotyped by Allele-Specific PCR (AS-PCR) method by using specific primers that were designed and the association between genotype and allele frequencies in cases and controls were estimated.Results: There was no significant association between APE1 GENE POLYMORPHISM at codon 148 in case and control groups.Conclusion: No significant association was found between the Asp148Glu POLYMORPHISM and idiopathic MALE INFERTILITY.

Cites

No record.

References

No record.

Cite

APA: Copy

YOUSEFI, M., SALEHI, Z., MASHAYEKHI, F., & BAHADORI, M.H.. (2015). ASSOCIATION OF APE1 GENE ASP148GLU POLYMORPHISM AND IDIOPATHIC MALE INFERTILITY. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 17(2 (54)), 87-91. SID. https://sid.ir/paper/79429/en

Vancouver: Copy

YOUSEFI M., SALEHI Z., MASHAYEKHI F., BAHADORI M.H.. ASSOCIATION OF APE1 GENE ASP148GLU POLYMORPHISM AND IDIOPATHIC MALE INFERTILITY. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2015;17(2 (54)):87-91. Available from: https://sid.ir/paper/79429/en

IEEE: Copy

M. YOUSEFI, Z. SALEHI, F. MASHAYEKHI, and M.H. BAHADORI, “ASSOCIATION OF APE1 GENE ASP148GLU POLYMORPHISM AND IDIOPATHIC MALE INFERTILITY,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 2 (54), pp. 87–91, 2015, [Online]. Available: https://sid.ir/paper/79429/en

Related Journal Papers