ASSOCIATION OF INTERLEUKIN-18 GENE POLYMORPHISM -137G/C WITH ALLERGIC RHINITIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

RAMAZI SH.; KHAZRAEI H.R.; MOTOVALIBASHI M.; IZIY E.; HASHEMZADE CHALESHTORI M.; ABOLHASSANI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2015 | Volume:17 | Issue:2 (54) Page(s): 82-86

Download Full-Text

Persian Verion

View:

858

Download:

Cites:

Information Journal Paper

Title

ASSOCIATION OF INTERLEUKIN-18 GENE POLYMORPHISM -137G/C WITH ALLERGIC RHINITIS

Author(s)

Keywords

ALLERGIC RHINITISQ2

INTERLEUKIN-18Q2

POLYMORPHISMQ2

Abstract

Background and Objective: The INTERLEUKIN-18 (IL-18) gene on chromosome 11 has been suggested as a susceptibility factor for allergies. It is a member of the IL-1 family that was originally described as interferon (IFN-g)–inducing factor. IL-18 might initiate Th2 responses with production of IgE via the stimulation of IL-4 and IL-13 synthesis in mast cells and in basophil and eosinophil recruitment, such as allergic inflammation. This study was done to assess the association of INTERLEUKIN-18 gene POLYMORPHISM -137G/C with ALLERGIC RHINITIS.Methods: This case-control study was performed on 293 ALLERGIC RHINITIS patients and 218 healthy control volunteers. The IL-18 POLYMORPHISM was analyzed by polymerase chain reaction and restriction fragment length POLYMORPHISM (PCR-RFLP) analysis.Results: The frequency of the GG, GC and CC genotypes were 64.2%, 32.1% and 3.7% in healthy controls and 60.1%, 35.5% and 4.4% in ALLERGIC RHINITIS patients, respectively. This diference was not significant.Conclusion: This study suggests that IL-18 POLYMORPHISM gene -137G/C may not be participated as a risk factor in the pathogenesis of ALLERGIC RHINITIS.

Cites

No record.

References

Cite

APA: Copy

RAMAZI, SH., KHAZRAEI, H.R., MOTOVALIBASHI, M., IZIY, E., HASHEMZADE CHALESHTORI, M., & ABOLHASSANI, M.. (2015). ASSOCIATION OF INTERLEUKIN-18 GENE POLYMORPHISM -137G/C WITH ALLERGIC RHINITIS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 17(2 (54)), 82-86. SID. https://sid.ir/paper/79443/en

Vancouver: Copy

RAMAZI SH., KHAZRAEI H.R., MOTOVALIBASHI M., IZIY E., HASHEMZADE CHALESHTORI M., ABOLHASSANI M.. ASSOCIATION OF INTERLEUKIN-18 GENE POLYMORPHISM -137G/C WITH ALLERGIC RHINITIS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2015;17(2 (54)):82-86. Available from: https://sid.ir/paper/79443/en

IEEE: Copy

SH. RAMAZI, H.R. KHAZRAEI, M. MOTOVALIBASHI, E. IZIY, M. HASHEMZADE CHALESHTORI, and M. ABOLHASSANI, “ASSOCIATION OF INTERLEUKIN-18 GENE POLYMORPHISM -137G/C WITH ALLERGIC RHINITIS,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 2 (54), pp. 82–86, 2015, [Online]. Available: https://sid.ir/paper/79443/en

Related Journal Papers