EFFECT OF HYSSOPUS OFFICINALIS LEAVES ALCOHOLIC EXTRACT ON MOTOR NEURON DENSITY IN ANTERIOR HORN AFTER SCIATIC NERVE COMPRESSION IN RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

TEHRANIPOUR M.; LAGZIAN A.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2017 | Volume:18 | Issue:4 (60) Page(s): 36-41

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

588

Download:

Cites:

Information Journal Paper

Title

EFFECT OF HYSSOPUS OFFICINALIS LEAVES ALCOHOLIC EXTRACT ON MOTOR NEURON DENSITY IN ANTERIOR HORN AFTER SCIATIC NERVE COMPRESSION IN RATS

Author(s)

TEHRANIPOUR M. | LAGZIAN A. | Issue Writer Certificate

Keywords

HYSSOPUS OFFICINALISQ1

NEURONQ2

SCIATIC NERVEQ3

STEREOLOGQ3

RATQ2

Abstract

Background and Objective: The degeneration of motor NEURON in anterior horn of spinal cord can be caused by compression. HYSSOPUS OFFICINALIS of Laminacea family demonstrate antioxidant and antiinflammation effects. This study was done to evaluate the effect of alcoholic extract of HYSSOPUS OFFICINALISleaves, on motor NEURON in spinal cord after SCIATIC NERVE compression in male RATs.Methods: In this experimental research, 60 male wistar RATs were randomly allocated into six groups including; control, compression, and compression+treatment (25, 50, 75, 100 mg/kg/bw). In order to induce compression, SCIATIC NERVE of right leg was exposed to compression for 60 second using locker pincers. Extract injected intraperitoneally in the first and second week after compression.28 days after compression under profusion method, the lumber spinal cord was sampled. The density of motor NEURONs (9-20 micron) was measured using dissector and STEREOLOGical method.Results: Density of NEURONs in compression group (611±34) significantly reduced compared to the control group (1658±30) (P<0.05). Moreover, NEURONal density was significantly increased in 25 (1179±22), 50 (1260±20), 75 (1350±15) and 100 (1120±10) mg/kg/bw doses in treatment groups in compared to the compression group (P<0.05).Conclusion: Alcoholic extract of HYSSOPUS OFFICINALIS leaves exhibite neuroprotective effect on NEURONs in anterior horn of the spinal cord after injury. This effect probably is related to the antioxidant and anti inflammation properties in alcoholic extract of HYSSOPUS OFFICINALIS, dose dependly.

Cites

No record.

References

No record.

Cite

APA: Copy

TEHRANIPOUR, M., & LAGZIAN, A.. (2017). EFFECT OF HYSSOPUS OFFICINALIS LEAVES ALCOHOLIC EXTRACT ON MOTOR NEURON DENSITY IN ANTERIOR HORN AFTER SCIATIC NERVE COMPRESSION IN RATS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 18(4 (60) ), 36-41. SID. https://sid.ir/paper/79529/en

Vancouver: Copy

TEHRANIPOUR M., LAGZIAN A.. EFFECT OF HYSSOPUS OFFICINALIS LEAVES ALCOHOLIC EXTRACT ON MOTOR NEURON DENSITY IN ANTERIOR HORN AFTER SCIATIC NERVE COMPRESSION IN RATS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;18(4 (60) ):36-41. Available from: https://sid.ir/paper/79529/en

IEEE: Copy

M. TEHRANIPOUR, and A. LAGZIAN, “EFFECT OF HYSSOPUS OFFICINALIS LEAVES ALCOHOLIC EXTRACT ON MOTOR NEURON DENSITY IN ANTERIOR HORN AFTER SCIATIC NERVE COMPRESSION IN RATS,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 18, no. 4 (60) , pp. 36–41, 2017, [Online]. Available: https://sid.ir/paper/79529/en

Related Journal Papers