EFFECT OF ALCOHOLIC EXTRACT OF GINGER DURING FETAL LIFE AND BREASTFEEDING ON SERUM LEVEL OF TESTOSTERONE, LH, FSH AND SPERMATOGENIC CELLS LINE IN MALE MATURE OFFSPRING RATS

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HOSSEINI S.E.; JAHANDIDE A.; MEHRABANI D.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Journal of Gorgan University of Medical Sciences Year:2015 | Volume:17 | Issue:1 (53) Page(s): 29-35

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Title

EFFECT OF ALCOHOLIC EXTRACT OF GINGER DURING FETAL LIFE AND BREASTFEEDING ON SERUM LEVEL OF TESTOSTERONE, LH, FSH AND SPERMATOGENIC CELLS LINE IN MALE MATURE OFFSPRING RATS

Author(s)

HOSSEINI S.E. | JAHANDIDE A. | MEHRABANI D. | Issue Writer Certificate

Keywords

GINGERQ2

TESTOSTERONEQ2

LUTEINIZING HORMONEQ2

FOLLICLE STIMULATING HORMONEQ3

SPERMATOGENIC CELL LINEQ2

RATQ2

Abstract

Background and Objective: GINGER as a medicinal herb is used as a food flavoring and thraphy of many diseases including infertility and male sexual disabilities. This study was carried out to evaluate the effect of alcoholic extract of GINGER during fetal life and breastfeeding on serum level of TESTOSTERONE, LH, FSH and SPERMATOGENIC CELL LINEs in male mature offspring RATs.Methods: In this experimental study, 72 female adult mice were randomly allocated into the 9 groups, including: control group (no treatment), sham groups including neonatal and perinatal groups which were received normal salin (0.5 ml daily) and 6 interventional groups. Animals in interventional groups were received doses of 50, 100 and 200 mg/kg/bw of alcoholic extract of GINGER, during neonatal and perinatal period, orally. After puberty eight male RATs from each group were sacrified. Serum level of TESTOSTERONE, LH, FSH were measeared and then by isolating testes, the cell numbers of leydig, sertoli, spermatogonia, spermatocyte and spermatid were counted.Results: The extract of GINGER dose-dependently significantly increased the level of TESTOSTERONE (P<0.05) and the number of spermatogenic cells in compared to controls (P<0.05). The dosage of 100 and 200 mg/kg/bw of alcoholic extract of GINGER significantly reduced the FSH and LH in compared to controls (P<0.05).Conclusion: The oral consumption of GINGER during pregnancy and lactation dose-dependently increase the level of TESTOSTERONE and the number of spermatogenic cells.

Cites

EFFECT OF CELL-PHONE RADIATION IN PREGNANCY ON SERUM LEVELS OF SEXUAL HORMONES AND DYNASTIC CELLS IN ADULT FEMALE OFFSPRING IN RATS

References

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APA: Copy

HOSSEINI, S.E., JAHANDIDE, A., & MEHRABANI, D.. (2015). EFFECT OF ALCOHOLIC EXTRACT OF GINGER DURING FETAL LIFE AND BREASTFEEDING ON SERUM LEVEL OF TESTOSTERONE, LH, FSH AND SPERMATOGENIC CELLS LINE IN MALE MATURE OFFSPRING RATS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 17(1 (53)), 29-35. SID. https://sid.ir/paper/79690/en

Vancouver: Copy

HOSSEINI S.E., JAHANDIDE A., MEHRABANI D.. EFFECT OF ALCOHOLIC EXTRACT OF GINGER DURING FETAL LIFE AND BREASTFEEDING ON SERUM LEVEL OF TESTOSTERONE, LH, FSH AND SPERMATOGENIC CELLS LINE IN MALE MATURE OFFSPRING RATS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2015;17(1 (53)):29-35. Available from: https://sid.ir/paper/79690/en

IEEE: Copy

S.E. HOSSEINI, A. JAHANDIDE, and D. MEHRABANI, “EFFECT OF ALCOHOLIC EXTRACT OF GINGER DURING FETAL LIFE AND BREASTFEEDING ON SERUM LEVEL OF TESTOSTERONE, LH, FSH AND SPERMATOGENIC CELLS LINE IN MALE MATURE OFFSPRING RATS,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 1 (53), pp. 29–35, 2015, [Online]. Available: https://sid.ir/paper/79690/en

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