HOMOCYSTEINE AND HIGH SENSITIVITY C -REACTIVE PROTEIN IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS, AND THEIR RELATION WITH DISEASES ACTIVITY AND CARDIOVASCULAR RISK FACTORS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SEDIGHY S.; SADANI S.; REZAII YAZDI Z.; HATEF M.R.; TAVAKOLI AFSHAR J.; AZARPAZHOH M.R.; AGHAI M.; ESMAEILI H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Gorgan University of Medical Sciences Year:2011 | Volume:13 | Issue:1 (37) Page(s): 44-50

Download Full-Text

Persian Verion

View:

964

Download:

Cites:

Information Journal Paper

Title

HOMOCYSTEINE AND HIGH SENSITIVITY C -REACTIVE PROTEIN IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS, AND THEIR RELATION WITH DISEASES ACTIVITY AND CARDIOVASCULAR RISK FACTORS

Author(s)

Keywords

SYSTEMIC LUPUS ERYTHEMATOSUSQ2

HOMOCYSTEINEQ2

HSCRPQ2

DISEASE ACTIVITYQ2

Abstract

Background and Objective: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) is an inflammatory multi-system disease with an unknown origin. In patients with lupus disease cardiovascular events is an important cause of mortality and morbidity. This study carried out to measurement of high sensitivity C -reactive protein (HsCRP) and HOMOCYSTEINE in patients with SLE and their relation with diseases activity and cardiovascular risk factors.Materials and Methods: This case control study carried out on 60 patients (55 females and 5 males) with lupus disease which referred to Clinical Research Center of Rheumatology, Mashhad, Iran and 30 controls (26 females and 4 males) during 2007-08. Information of subjects were gathered using SLEDAI questionare. HSCRP and HOMOCYSTEINE of subjects were measured. The level of low density lipoprotein (LDL), Triglycerid, hypertension and Body mass index (BMI) was assessed. SYSTEMIC LUPUS ERYTHEMATOSUS activity was assessed by using SLEDAI so that if the score was higher than 10, lupus was called as active disease.Results: Mean age was 28.8±10.3 and 33.8±9.13 years in SLE and control groups respectively. The mean of HSCRP in SLE patients were 3±2.42 mg/dl versus in controls were 1.58±2.1. The serum level of HOMOCYSTEINE were 12.3±1.93 mmol/L and 24±8.13 mmol/L in SLE patients and controls (P<0.001). Mean DISEASE ACTIVITY was 15.37. There was no any associtation between HOMOCYSTEINE and HSCRP and DISEASE ACTIVITY. LDL, Triglycerid, hypertension had significant association with homocystein (P<0.05). BMI and Triglycerid had significant association with HSCRP (P<0.05).Conclusion: This study showed that there is no linear significant corrolation between HOMOCYSTEINE, HSCRP and DISEASE ACTIVITY, but there is significant corrolation between increase of HOMOCYSTEINE and HSCRP and cardiovascular risk factors.

Cites

No record.

References

No record.

Cite

APA: Copy

SEDIGHY, S., SADANI, S., REZAII YAZDI, Z., HATEF, M.R., TAVAKOLI AFSHAR, J., AZARPAZHOH, M.R., AGHAI, M., & ESMAEILI, H.. (2011). HOMOCYSTEINE AND HIGH SENSITIVITY C -REACTIVE PROTEIN IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS, AND THEIR RELATION WITH DISEASES ACTIVITY AND CARDIOVASCULAR RISK FACTORS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 13(1 (37)), 44-50. SID. https://sid.ir/paper/79711/en

Vancouver: Copy

SEDIGHY S., SADANI S., REZAII YAZDI Z., HATEF M.R., TAVAKOLI AFSHAR J., AZARPAZHOH M.R., AGHAI M., ESMAEILI H.. HOMOCYSTEINE AND HIGH SENSITIVITY C -REACTIVE PROTEIN IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS, AND THEIR RELATION WITH DISEASES ACTIVITY AND CARDIOVASCULAR RISK FACTORS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;13(1 (37)):44-50. Available from: https://sid.ir/paper/79711/en

IEEE: Copy

S. SEDIGHY, S. SADANI, Z. REZAII YAZDI, M.R. HATEF, J. TAVAKOLI AFSHAR, M.R. AZARPAZHOH, M. AGHAI, and H. ESMAEILI, “HOMOCYSTEINE AND HIGH SENSITIVITY C -REACTIVE PROTEIN IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS, AND THEIR RELATION WITH DISEASES ACTIVITY AND CARDIOVASCULAR RISK FACTORS,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 13, no. 1 (37), pp. 44–50, 2011, [Online]. Available: https://sid.ir/paper/79711/en

Related Journal Papers