EFFECT OF APRICOT TREE RESIN HYDROETHANOLIC EXTRACT ON SKIN WOUND HEALING IN RATS

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JAVADABADI KARIM; SADOGHI MEHRANGIZ; TAVAFI MAJID; GHOLAMI MOHAMMAD REZA

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Journal: Yafteh Year:2017 | Volume:18 | Issue:4 (70) Page(s): 98-103

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Information Journal Paper

Title

EFFECT OF APRICOT TREE RESIN HYDROETHANOLIC EXTRACT ON SKIN WOUND HEALING IN RATS

Author(s)

JAVADABADI KARIM | SADOGHI MEHRANGIZ | TAVAFI MAJID | GHOLAMI MOHAMMAD REZA | Issue Writer Certificate

Keywords

APRICOT TREE RESINQ1

WOUND HEALINGQ3

RATQ2

Abstract

Background: Impairment of WOUND HEALING in chronic diseases is a therapeutic challenge. In terms of anti-inflammatory and regenerative effects of hydro-alcoholic extract of apricot gum tree this extract used on skin WOUND HEALING in RATs.Materials and Methods: 28 Wistar male RATs were divided into four groups: group I, normal without surgery, group II, control group without treatment, group III, a wound treatment with Vaseline, and group I˅, wound care therapy APRICOT TREE RESIN extract. In the treated and placebo groups after anesthesia applied induction circular wound area of 280 square millimeters behind RATs, but treated groups continued treatment for 21 days. Daily treatment was done with hydro-alcoholic extract of apricot tree gum. Wound size is measured every day by analyzing digital images for 21 days and then RATs killed and samples were fixed in formalin. Slices were stained with hematoxylin and eosin. Tissue sections were studied qualitatively and quantitatively, to check regeneration of cells, the collagen fibers, angiogenesis, and distribution of inflammatory cells. Normal data analyzed using Tukey test and data with non-normal distribution were compared between groups by Mann-Whitney test.Results: Use of APRICOT TREE RESIN, reduces the blood vessels from the second week onwards, reduction of inflammatory cells and increased collagen fibers and tissue epithelialization.Conclusion: APRICOT TREE RESIN extract can promote WOUND HEALING faster made substantial improvements.

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APA: Copy

JAVADABADI, KARIM, SADOGHI, MEHRANGIZ, TAVAFI, MAJID, & GHOLAMI, MOHAMMAD REZA. (2017). EFFECT OF APRICOT TREE RESIN HYDROETHANOLIC EXTRACT ON SKIN WOUND HEALING IN RATS. YAFTEH, 18(4 (70)), 98-103. SID. https://sid.ir/paper/79780/en

Vancouver: Copy

JAVADABADI KARIM, SADOGHI MEHRANGIZ, TAVAFI MAJID, GHOLAMI MOHAMMAD REZA. EFFECT OF APRICOT TREE RESIN HYDROETHANOLIC EXTRACT ON SKIN WOUND HEALING IN RATS. YAFTEH[Internet]. 2017;18(4 (70)):98-103. Available from: https://sid.ir/paper/79780/en

IEEE: Copy

KARIM JAVADABADI, MEHRANGIZ SADOGHI, MAJID TAVAFI, and MOHAMMAD REZA GHOLAMI, “EFFECT OF APRICOT TREE RESIN HYDROETHANOLIC EXTRACT ON SKIN WOUND HEALING IN RATS,” YAFTEH, vol. 18, no. 4 (70), pp. 98–103, 2017, [Online]. Available: https://sid.ir/paper/79780/en

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