THE EFFECT OF INTRAPERITONEALLY INJECTION OF CRYSTAL METH ON PITUITARY-GONAD AXIS IN ADULT MALE RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HATAMI HOMEIRA; KHAJEHNASIRI NAZLI

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Yafteh Year:2015 | Volume:17 | Issue:2 (64) Page(s): 81-89

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

707

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF INTRAPERITONEALLY INJECTION OF CRYSTAL METH ON PITUITARY-GONAD AXIS IN ADULT MALE RATS

Author(s)

HATAMI HOMEIRA | KHAJEHNASIRI NAZLI | Issue Writer Certificate

Keywords

CRYSTAL METHQ2

TESTOSTERONEQ2

FSH AND LHQ2

PITUITARYQ2

GONAD AXISQ2

Abstract

Background: Psychostimulant amphetamine (Ecstasy and CRYSTAL METH or n-methyl-1- phenyl-propan-2- amine) abuse has been prevalent among the youth of Iran in recant years. These substances have many adverse and destructive effects on several organs. Therefore, this study was done to determine the effect of CRYSTAL METH on PITUITARY-gonadal axis in adult male rats.Material and Methods: 28 male adult rats were divided into four groups; normal control group, and 5, 10 and 15 mg/kg bw CRYSTAL METH-treatment groups. Animals in the CRYSTAL METH-treated groups received 5, 10 and 15 mg/kg bw of CRYSTAL METH intraperitoneally for seven days. After 7 days, blood sample was taken from the left ventricle of the animal's heart and LH, FSH and TESTOSTERONE concentration were measured using ELISA kit. The SPSS-16 statistical software was used to analyze data. All data were analyzed by one-way analysis of variance (ANOVA) and the differences were considered significant at the p<0.05 level.Results: TESTOSTERONE hormone concentration significantly increased in experimental groups (10 and 15 mg/kg bw) in comparison with control group (P<0.05). Concentrations of FSH AND LH in the experimental groups (5, 10 and 15 mg/kg bw) significantly reduced in comparison with control group (P<0.05).Conclusion: According to the hormonal examinations, we concluded that the use of CRYSTAL METH causes destructive effects on the male PITUITARY-gonadal axis.

Cites

No record.

References

No record.

Cite

APA: Copy

HATAMI, HOMEIRA, & KHAJEHNASIRI, NAZLI. (2015). THE EFFECT OF INTRAPERITONEALLY INJECTION OF CRYSTAL METH ON PITUITARY-GONAD AXIS IN ADULT MALE RATS. YAFTEH, 17(2 (64)), 81-89. SID. https://sid.ir/paper/80164/en

Vancouver: Copy

HATAMI HOMEIRA, KHAJEHNASIRI NAZLI. THE EFFECT OF INTRAPERITONEALLY INJECTION OF CRYSTAL METH ON PITUITARY-GONAD AXIS IN ADULT MALE RATS. YAFTEH[Internet]. 2015;17(2 (64)):81-89. Available from: https://sid.ir/paper/80164/en

IEEE: Copy

HOMEIRA HATAMI, and NAZLI KHAJEHNASIRI, “THE EFFECT OF INTRAPERITONEALLY INJECTION OF CRYSTAL METH ON PITUITARY-GONAD AXIS IN ADULT MALE RATS,” YAFTEH, vol. 17, no. 2 (64), pp. 81–89, 2015, [Online]. Available: https://sid.ir/paper/80164/en

Related Journal Papers