THE RELATIONSHIP BETWEEN SURVIVIN EXPRESSION IN THYROID FOLLICULAR ADENOMA AND CARCINOMA

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HAGHPANAH V.; SHOUSHTARIZADEH P.; LASHKARI A.; HESHMAT RAMIN; ARDESHIR LARIJANI MOHAMMAD BAGHER; TAVANGAR S.M.

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Journal: Journal of Sabzevar University of Medical Sciences Year:2007 | Volume:14 | Issue:1 (43) Page(s): 32-37

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Title

THE RELATIONSHIP BETWEEN SURVIVIN EXPRESSION IN THYROID FOLLICULAR ADENOMA AND CARCINOMA

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Keywords

THYROID CANCERQ2

FOLLICULAR NEOPLASMQ3

APOPTOSISQ3

SURVIVINQ2

Abstract

Background and Purpose: SURVIVINg is one of the eight members of the human inhibitors of APOPTOSIS (IAP), which appears to be differentially expressed in cancer cells. This study was conducted to evaluate the clinical usefulness of SURVIVIN immunostaining to distinguish between follicular adenoma and carcinoma of thyroid.Methods and Materials: This study was a cross-sectional descriptive-analytical research. The study population was tissue samples from surgery patients at Shariati Hospital in Tehran, Iran. All samples were studied through immunohistochemical staining for SURVIVINg.Results: SURVIVINg expression was significantly (p<0.005) higher in patients with follicular carcinoma diagnosis than those with adenoma. Odds ratio of follicular carcinoma for SURVIVINg expression was reported to be 21.375 (95% CI: 3.283-139.177).Conclusion: The study indicated that SURVIVINg can play an effective role in distinguishing follicular thyroid adenoma from follicular thyroid carcinoma.

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APA: Copy

HAGHPANAH, V., SHOUSHTARIZADEH, P., HESHMAT, RAMIN, LASHKARI, A., ARDESHIR LARIJANI, MOHAMMAD BAGHER, & TAVANGAR, S.M.. (2007). THE RELATIONSHIP BETWEEN SURVIVIN EXPRESSION IN THYROID FOLLICULAR ADENOMA AND CARCINOMA. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 14(1 (43)), 32-37. SID. https://sid.ir/paper/82288/en

Vancouver: Copy

HAGHPANAH V., SHOUSHTARIZADEH P., HESHMAT RAMIN, LASHKARI A., ARDESHIR LARIJANI MOHAMMAD BAGHER, TAVANGAR S.M.. THE RELATIONSHIP BETWEEN SURVIVIN EXPRESSION IN THYROID FOLLICULAR ADENOMA AND CARCINOMA. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;14(1 (43)):32-37. Available from: https://sid.ir/paper/82288/en

IEEE: Copy

V. HAGHPANAH, P. SHOUSHTARIZADEH, RAMIN HESHMAT, A. LASHKARI, MOHAMMAD BAGHER ARDESHIR LARIJANI, and S.M. TAVANGAR, “THE RELATIONSHIP BETWEEN SURVIVIN EXPRESSION IN THYROID FOLLICULAR ADENOMA AND CARCINOMA,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 14, no. 1 (43), pp. 32–37, 2007, [Online]. Available: https://sid.ir/paper/82288/en

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