STUDY OF THE HISTOLOGICAL OF MOUSE INTERVERTEBRAL DISC DEVELOPMENT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JALALI MAHDI; NIKRAVESH M.R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2007 | Volume:14 | Issue:1 (43) Page(s): 44-52

Download Full-Text

Persian Verion

View:

1,288

Download:

Cites:

Information Journal Paper

Title

STUDY OF THE HISTOLOGICAL OF MOUSE INTERVERTEBRAL DISC DEVELOPMENT

Author(s)

JALALI MAHDI | NIKRAVESH M.R. | Issue Writer Certificate

Keywords

DEVELOPMENTQ2

INTERVERTEBRAL DISKQ3

NOTOCHORDQ4

MOUSEQ2

Abstract

Background and Purpose: At least two different elements can be detected in the structure of mature intervertebral disc. The central portion contains nucleus pulpous. Its few cells being embedded in gel form material. The outer protein, however, is called annulus fibroses, composed of concentric layers of intertwined annulus bands. Although the major anatomical structures of intervertebral disc are well known, there are little information on the DEVELOPMENT of its components such as cell type and extracellul matrix. Therefore, this study was conducted to study the histological changes in the DEVELOPMENT of intervertebral disc in MOUSE.Methods and Materials: In this study, collagen fiber appearance and cellular differentiation were studied using serial section and histological staining methods in the course of intervertebral disc DEVELOPMENT in MOUSE embryo. Results: The findings indicated that from the 12th day of gestation, the NOTOCHORD starts getting separated from the floor plate of neural tube. Gradually on the next days, as mesenchyme cells get condensed around, patterns of intervertebral disc differentiation can be observed, leading to disc DEVELOPMENT toward the end of gestation. Throughout this process, the NOTOCHORD degenerates. Theses changes start from the middle portion of NOTOCHORD and proceeds towards head and tail. Then vertebral bodies are forward in portions with degenerated NOTOCHORD changes.Conclusion: During the DEVELOPMENT changes of intervertebral disc, remnants of NOTOCHORD form nucleus pulpous in the intervertebral disc. However, the mesenchyme surrounding it (forthcoming annulus fibrosus) consist of structurally dissimilar regions. Under these circumstances, the outer portion is made up of highly-densed collagen material but in the inner portion, remnants of embryonic hyaline cartilage and collagen fibers can be detected.

Cites

No record.

References

No record.

Cite

APA: Copy

JALALI, MAHDI, & NIKRAVESH, M.R.. (2007). STUDY OF THE HISTOLOGICAL OF MOUSE INTERVERTEBRAL DISC DEVELOPMENT. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 14(1 (43)), 44-52. SID. https://sid.ir/paper/82296/en

Vancouver: Copy

JALALI MAHDI, NIKRAVESH M.R.. STUDY OF THE HISTOLOGICAL OF MOUSE INTERVERTEBRAL DISC DEVELOPMENT. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;14(1 (43)):44-52. Available from: https://sid.ir/paper/82296/en

IEEE: Copy

MAHDI JALALI, and M.R. NIKRAVESH, “STUDY OF THE HISTOLOGICAL OF MOUSE INTERVERTEBRAL DISC DEVELOPMENT,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 14, no. 1 (43), pp. 44–52, 2007, [Online]. Available: https://sid.ir/paper/82296/en

Related Journal Papers