THE EFFECT OF SALMETEROL ON SOME PARAMETERS OF PULMONARY VENTILATION IN SMOKERS AND NON- SMOKERS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

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GOLMOHAMMADI R.; NORI G.

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Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2014 | Volume:21 | Issue:2 Page(s): 302-309

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Title

THE EFFECT OF SALMETEROL ON SOME PARAMETERS OF PULMONARY VENTILATION IN SMOKERS AND NON- SMOKERS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Author(s)

GOLMOHAMMADI R. | NORI G. | Issue Writer Certificate

Keywords

SALMETEROLQ2

COPDQ3

CIGARETTEQ2

LUNGQ2

SMOKINGQ2

Abstract

Background: There are many factors that effect on the LUNGs capacity and treatment process in chronic obstructive pulmonary disease (COPD). SMOKING, as a risk factor, is important in this process. The aim of this study was to evaluate the efficacy of SALMETEROL on some parameters of pulmonary ventilation in smokers and non-smokers patients with COPD.Materials and Methods: This desiccative analytical study was done on 117 patients with respiratory symptoms of COPD who had referred to an internist during 2010-2013 in Sabzevar city, Iran. Data collection methods include observation, clinical symptoms, and respiratory test (spirometry) that was performed by a physician. Before and after SALMETEROL inhalation, pulmonary function tests were performed, and pulmonary parameters FEVI, FVC, FEV1% and PEF were measured and recorded. Data were analyzed using paired t test, and independent t test.Results: Of 117 patients 75 (64%) were male and 42 (36%) were female. The mean age of smokers and non-smokers was 42.36±18.20 and 50.14±18.56, respectively; which was statistically significan (P<0.03). FEV1% was significantly different in COPD patients before and after SALMETEROL inhalation (97.44±10.84 and 94.75±10.81, respectively) (P<0.04). In smokers, before SALMETEROL inhalation, the mean forced expiratory volume in the first second (FEVI), was lower than nonsmokers, but after SALMETEROL inhalation, was higher than nonsmokers, but not significant. Also, after SALMETEROL inhalation, FEVI% was higher in non-smokers compared with smokers.Conclusion: In smokers, COPD onset is 8 years earlier than non-smokers, and SALMETEROL inhalation decreases FEVI% in COPD patients.

Cites

ASSESSING OF PARAMETERS ASSOCIATED WITH SPIROMETER INDUSTRIAL WORKERS ADMITTED FOR EMPLOYMENT EXAMINATIONS TUYSERKAN CITY IN 2013

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APA: Copy

GOLMOHAMMADI, R., & NORI, G.. (2014). THE EFFECT OF SALMETEROL ON SOME PARAMETERS OF PULMONARY VENTILATION IN SMOKERS AND NON- SMOKERS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 21(2), 302-309. SID. https://sid.ir/paper/82399/en

Vancouver: Copy

GOLMOHAMMADI R., NORI G.. THE EFFECT OF SALMETEROL ON SOME PARAMETERS OF PULMONARY VENTILATION IN SMOKERS AND NON- SMOKERS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;21(2):302-309. Available from: https://sid.ir/paper/82399/en

IEEE: Copy

R. GOLMOHAMMADI, and G. NORI, “THE EFFECT OF SALMETEROL ON SOME PARAMETERS OF PULMONARY VENTILATION IN SMOKERS AND NON- SMOKERS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 2, pp. 302–309, 2014, [Online]. Available: https://sid.ir/paper/82399/en

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