COMPARING THE EFFECTS OF CRYSTALLOID WITH EPHEDRINE+ CRYSTALLOID ON MATERNAL HYPERTENSION IN ELECTIVE CESAREAN SECTION UNDER SPINAL ANESTHESIA

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NOUROUZI HAMID REZA; SHAHRYARI ALI

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Journal: Journal of Sabzevar University of Medical Sciences Year:2009 | Volume:15 | Issue:4 (50) Page(s): 192-199

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Information Journal Paper

Title

COMPARING THE EFFECTS OF CRYSTALLOID WITH EPHEDRINE+ CRYSTALLOID ON MATERNAL HYPERTENSION IN ELECTIVE CESAREAN SECTION UNDER SPINAL ANESTHESIA

Author(s)

NOUROUZI HAMID REZA | SHAHRYARI ALI | Issue Writer Certificate

Keywords

SPINAL ANESTHESIAQ2

HYPOTENSIONQ3

EPHEDRINEQ3

CRYSTALLOIDQ2

CAESAREAN SECTIONQ3

Abstract

Background and Purpose: Pretreatment with CRYSTALLOID has not been able to maintain blood pressure during elective cesarean section under SPINAL ANESTHESIA, and it seems that prophylactic EPHEDRINE+crystalloid can reduce HYPOTENSION and administration of high doses of EPHEDRINE. The aim of the present study is to compare the effects of EPHEDRINE+crystalloid pretreatment with CRYSTALLOID alone on blood pressure during elective CAESAREAN SECTION under SPINAL ANESTHESIA.Methods and Materials: In this double blind clinical trial, we enrolled 72 women admitted to Ali-ebne-Abitaleb hospital in Zahedan, Iran, who were candidates for elective CAESAREAN SECTION under SPINAL ANESTHESIA in 2006,and divided them into group A (ephedrine+cistalloid) and group B (placebo+cristalloid) by convenience sampling. Infusion with 10ml/Kg of ringer solution was made within 10-15min before the initiation of spinal block in both groups. Also, 10mg EPHEDRINE in group A and placebo in group B were added to the solution. After newborn delivery, 20 IU oxitocin and 2mg midazolam were administered to all patients. Systolic BP, HR, nausea, vomiting, level of spinal block and neonatal Apgar were recorded and analyzed by Chi-square and student's t-tests (P<0.05 was considered as statistically significant).Results: Episode of HYPOTENSION occurred in 25% of group A and 55.6% of group B patients, suggesting a statistically significant difference between the two groups (P=0.008). However, there were no significant differences between the two groups in their mean systolic BP after intervention (105.61±7.13 in group B versus 107.89±9.84 in group A, in 1-10min; also, 106.20±8.52 in group B versus 109.39±6.72 in group A, in 11-60min). Conclusion: Prophylactic infusion of EPHEDRINE±crystalloid is more effective than CRYSTALLOID pre-hydration in the prevention of HYPOTENSION during SPINAL ANESTHESIA for elective CAESAREAN SECTION.

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APA: Copy

NOUROUZI, HAMID REZA, & SHAHRYARI, ALI. (2009). COMPARING THE EFFECTS OF CRYSTALLOID WITH EPHEDRINE+ CRYSTALLOID ON MATERNAL HYPERTENSION IN ELECTIVE CESAREAN SECTION UNDER SPINAL ANESTHESIA. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 15(4 (50)), 192-199. SID. https://sid.ir/paper/82543/en

Vancouver: Copy

NOUROUZI HAMID REZA, SHAHRYARI ALI. COMPARING THE EFFECTS OF CRYSTALLOID WITH EPHEDRINE+ CRYSTALLOID ON MATERNAL HYPERTENSION IN ELECTIVE CESAREAN SECTION UNDER SPINAL ANESTHESIA. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;15(4 (50)):192-199. Available from: https://sid.ir/paper/82543/en

IEEE: Copy

HAMID REZA NOUROUZI, and ALI SHAHRYARI, “COMPARING THE EFFECTS OF CRYSTALLOID WITH EPHEDRINE+ CRYSTALLOID ON MATERNAL HYPERTENSION IN ELECTIVE CESAREAN SECTION UNDER SPINAL ANESTHESIA,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 15, no. 4 (50), pp. 192–199, 2009, [Online]. Available: https://sid.ir/paper/82543/en

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