DIAGNOSTIC VALIDITY OF ELECTROCARDIOGRAPHY COMPARED WITH ECHOCARDIOGRAPHY FOR DIAGNOSING LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH β- THALASSEMIA MAJOR

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NOURI NOUR MOHAMMAD; RAJAEI SH.

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Journal: Zahedan Journal of Research in Medical Sciences Year:2007 | Volume:9 | Issue:2 Page(s): 103-111

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Title

DIAGNOSTIC VALIDITY OF ELECTROCARDIOGRAPHY COMPARED WITH ECHOCARDIOGRAPHY FOR DIAGNOSING LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH β- THALASSEMIA MAJOR

Author(s)

NOURI NOUR MOHAMMAD | RAJAEI SH. | Issue Writer Certificate

Keywords

MAJOR THALASSEMIAQ3

LEFT VENTRICULAR HYPERTROPHYQ3

ELECTROCARDIOGRAPHYQ3

ECHOCARDIOGRAPHYQ3

Abstract

Background: LEFT VENTRICULAR HYPERTROPHY (L VH) is an important risk factor in determining cardiovascular disease prognosis. ECHOCARDIOGRAPHY (ECHO) is a sensitive and specific tool for detection of L VH but cost and operational consideration tend to limit its utility; in contrast, the ELECTROCARDIOGRAPHY (ECG) is widely available, expensive and less operator dependent. Since the comparison of diagnostic validity between ECG and ECHO for evaluating of L VH has not been well studied, this survey was carried out on a number of major b-thlassemia patients.Materials and Methods: This descriptive-analytical study was performed on 135 patients (including male and female) with major b- thalassemia over 8 years old. Patients with heart failure, valvular or structural heart disease, renal and endocrine disease and Hb<10g/dl were excluded.ECG and ECHO were performed 48 h after blood transfusion. ECG criteria of L VH and myocardial performance index (MPI) in ECHO were measured. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of ECG indexes were calculated separately for both sexes and compared with ECHO findings.Results: The patients included 64 (47/4 %) males and 71 (52/6 %) females. ECG indexes were found as follows: 70% sensitivity of the Sokolow-Lyon index, 14.3%; specificity, 90.3% PPV, 40% NPVand.Sensitivity of the Sokolow-Lyon-Rappaport, specificity, PPV, and NPV were 61.9%, 25/8%, 27/4%, 60%, respectively. Sensitivity of the Comell index was 66.6%. specificity13.3%, PPV 86% and NPV 4.7%, Sensitivity of the White-Bock index was 0%, specificity 100%, PPVO% and NPV was 68.9%. There was significant relationship between E{:G indexes and some ECHO parameters. In this study there was a reverse and significant relationship between left acceleration time (AT) and the Sokolow-Lyon-Rappaport index statistically (r = 0.181,p = 0.035). There was a significant direct relationship between left deceleration time (DT) and the Sokolow-Lyon- Rappaport index (r = 0.181, p = 0.036). A reverse significant relationship between right AT and the Sokolow-Lyon index was seen (r = 0.173, P = 0.044). A direct and significant relationship between diastolic inter ventricular septum diameter (IVSd) and the Sokolow-Lyon-Rappaport index was also observed (r = 0.186,P = 0.031).Conclusion: Thefindings of this study showed that ECG, compared with ECHO, has verylow diagnostic validity for L VH but ECG indexes has statistically significant relationship with some ECHO parameters (AT, DT, /VSd, LV/Dd) of left ventricular mass.

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APA: Copy

NOURI, NOUR MOHAMMAD, & RAJAEI, SH.. (2007). DIAGNOSTIC VALIDITY OF ELECTROCARDIOGRAPHY COMPARED WITH ECHOCARDIOGRAPHY FOR DIAGNOSING LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH β- THALASSEMIA MAJOR. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 9(2), 103-111. SID. https://sid.ir/paper/84267/en

Vancouver: Copy

NOURI NOUR MOHAMMAD, RAJAEI SH.. DIAGNOSTIC VALIDITY OF ELECTROCARDIOGRAPHY COMPARED WITH ECHOCARDIOGRAPHY FOR DIAGNOSING LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH β- THALASSEMIA MAJOR. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2007;9(2):103-111. Available from: https://sid.ir/paper/84267/en

IEEE: Copy

NOUR MOHAMMAD NOURI, and SH. RAJAEI, “DIAGNOSTIC VALIDITY OF ELECTROCARDIOGRAPHY COMPARED WITH ECHOCARDIOGRAPHY FOR DIAGNOSING LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH β- THALASSEMIA MAJOR,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 9, no. 2, pp. 103–111, 2007, [Online]. Available: https://sid.ir/paper/84267/en

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