BROAD SPECTRUM ANTIBACTERIAL ACTIVITY OF PERACETIC ACID (PERCIDIN)

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MORADI A.A.V.; SHAH MORADI MAHDI; GHAEMI EZAT ELAH; TABARAEI A.J.; SADEGH SHESHPOLI M.; BAZOURI M.; KOUHSARI H.

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Journal: Zahedan Journal of Research in Medical Sciences Year:2009 | Volume:11 | Issue:1 Page(s): 39-48

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Title

BROAD SPECTRUM ANTIBACTERIAL ACTIVITY OF PERACETIC ACID (PERCIDIN)

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Keywords

PERCIDINQ3

PERACETIC ACIDQ3

GRAM POSITIVE BACTERIAQ3

GRAM NEGATIVE BACTERIAQ3

MICQ2

MBCQ2

Abstract

Background: PERACETIC ACID (PERCIDIN) is a chemical compound that shows antimicrobial activity due to its high oxidizing potential. This study was designed to evaluate the efficiency of antibacterial activity of PERCIDIN and its spectrum by disc diffusion and MICrodilution methods.Materials and Methods: Standard strains and isolated bacteria from clinical specimens in the north of Iran were used in this work. Different dilutions of PERCIDINe and discs were prepared. Disc diffusion test was done and inhibition zone was measured. Finally, MIC and MBC was determined by MICrodilution methods.Results: Our results demonstrated highest susceptibility of Staphylococcus aureus strains that were sensitive and resistant to methiciline. Lower level of susceptibility to PERCIDIN was seen for Bacillus licheniformis. Inhibition zone for GRAM NEGATIVE BACTERIA was between 34 and 45 mm. Almost both MIC and MBC for GRAM POSITIVE BACTERIA was 2mg/ml and maximum amount obtained in Mycobacterium smegmatis and Entrococcus fecalis with 4mg/ml and 8mg/ml simultaneously. The MIC was 4mg/ml in GRAM NEGATIVE BACTERIA.Conclusion: The analysis of PERCIDIN antibacterial activity against different types of bacteria shows its wide antibacterial spectrum that covers gram-positive and gram-negative bacteria including standard and clinical isolated strains. The coincidence of most of the MIC and the MBC indicates the bactericidal activity for PERCIDIN. In brief, this work describes a broad-spectrum antibacterial activity of PERCIDIN and suggests use of this compound as a strong disinfectant in hospitals and elimination of bacteria from medical equipments.

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APA: Copy

MORADI, A.A.V., SHAH MORADI, MAHDI, GHAEMI, EZAT ELAH, TABARAEI, A.J., SADEGH SHESHPOLI, M., BAZOURI, M., & KOUHSARI, H.. (2009). BROAD SPECTRUM ANTIBACTERIAL ACTIVITY OF PERACETIC ACID (PERCIDIN). ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 11(1), 39-48. SID. https://sid.ir/paper/84319/en

Vancouver: Copy

MORADI A.A.V., SHAH MORADI MAHDI, GHAEMI EZAT ELAH, TABARAEI A.J., SADEGH SHESHPOLI M., BAZOURI M., KOUHSARI H.. BROAD SPECTRUM ANTIBACTERIAL ACTIVITY OF PERACETIC ACID (PERCIDIN). ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2009;11(1):39-48. Available from: https://sid.ir/paper/84319/en

IEEE: Copy

A.A.V. MORADI, MAHDI SHAH MORADI, EZAT ELAH GHAEMI, A.J. TABARAEI, M. SADEGH SHESHPOLI, M. BAZOURI, and H. KOUHSARI, “BROAD SPECTRUM ANTIBACTERIAL ACTIVITY OF PERACETIC ACID (PERCIDIN),” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 11, no. 1, pp. 39–48, 2009, [Online]. Available: https://sid.ir/paper/84319/en

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