STUDY ON THE FREQUENCY OF HYPERAMYLASEMIA IN PATIENTS AFFECTED BY INFLAMMATORY BOWEL DISEASE AND ITS RELATIONSHIP WITH EXTENT AND ACTIVITY OF THE DISEASE

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EBRAHIMI DARYANI N.; FOROUTAN H.; MAJIDI M.; BAHRAMI H.; HAGHPANAH BEHZAD; MIRMOUMEN SH.; MOHAMADI H.; NAYER HABIBI A.

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Journal: GOVARESH JOURNAL Year:2002 | Volume:7 | Issue:37-38 Page(s): 38-44

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Title

STUDY ON THE FREQUENCY OF HYPERAMYLASEMIA IN PATIENTS AFFECTED BY INFLAMMATORY BOWEL DISEASE AND ITS RELATIONSHIP WITH EXTENT AND ACTIVITY OF THE DISEASE

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AMYLASEQ4

IBDQ4

DISEASE ACTIVITYQ4

Abstract

Background: Serum AMYLASE elevation has been detected in some patients with inflammatory bowel diseases and recently some studies have elicited a relationship between AMYLASE elevation and disease extent and activity.Material and Methods: 212 patients (101 male and 100 female) with Inflammatory Bowel Disease (including 193 patients with UC and 19 patients with CD) whose diseases were confirmed by colonoscopy and histology were enrolled prospectively. Exclusion Criteria included: Pregnancy, CHF, Malignancy, Renal Failure, Diseases of Salivary Glands, Ruptured Peptic Ulcer, Peritonitis, and Cholecystitis. For all patients serum and urine AMYLASE levels were measured and a detailed questionnaire was filled.Results: HyperAMYLASEmia was observed in 16.0% of patients (15.5% of patients with UC and 21.0% of patients with CD). In 13.7% of patients (13.5% of UC patients and 15.8% of CD patients) urine AMYLASE elevation was detected. There was no significant relationship between serum/urine AMYLASE and disease extent, and activity, smoking habit, drug usage, extraintestinal involvement and history of colectomy. No significant association was found between serum AMYLASE and extent or activity of CD, too. We found a significant relationship between urine AMYLASE and activity, and not extent, of CD (p value: 0.005).Conclusion: An increase of serum/urine AMYLASE levels is seen in some of patients with inflammatory bowel disease; but the pathophysiology of this finding and its association with extent and activity of disease is open to further investigations.

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APA: Copy

EBRAHIMI DARYANI, N., FOROUTAN, H., MAJIDI, M., BAHRAMI, H., HAGHPANAH, BEHZAD, MIRMOUMEN, SH., MOHAMADI, H., & NAYER HABIBI, A.. (2002). STUDY ON THE FREQUENCY OF HYPERAMYLASEMIA IN PATIENTS AFFECTED BY INFLAMMATORY BOWEL DISEASE AND ITS RELATIONSHIP WITH EXTENT AND ACTIVITY OF THE DISEASE. GOVARESH JOURNAL, 7(37-38), 38-44. SID. https://sid.ir/paper/86076/en

Vancouver: Copy

EBRAHIMI DARYANI N., FOROUTAN H., MAJIDI M., BAHRAMI H., HAGHPANAH BEHZAD, MIRMOUMEN SH., MOHAMADI H., NAYER HABIBI A.. STUDY ON THE FREQUENCY OF HYPERAMYLASEMIA IN PATIENTS AFFECTED BY INFLAMMATORY BOWEL DISEASE AND ITS RELATIONSHIP WITH EXTENT AND ACTIVITY OF THE DISEASE. GOVARESH JOURNAL[Internet]. 2002;7(37-38):38-44. Available from: https://sid.ir/paper/86076/en

IEEE: Copy

N. EBRAHIMI DARYANI, H. FOROUTAN, M. MAJIDI, H. BAHRAMI, BEHZAD HAGHPANAH, SH. MIRMOUMEN, H. MOHAMADI, and A. NAYER HABIBI, “STUDY ON THE FREQUENCY OF HYPERAMYLASEMIA IN PATIENTS AFFECTED BY INFLAMMATORY BOWEL DISEASE AND ITS RELATIONSHIP WITH EXTENT AND ACTIVITY OF THE DISEASE,” GOVARESH JOURNAL, vol. 7, no. 37-38, pp. 38–44, 2002, [Online]. Available: https://sid.ir/paper/86076/en

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