CAUSES OF CIRRHOSIS IN A SERIES OF PATIENTS AT A UNIVERSITY HOSPITAL IN TEHRAN

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AZIMI K.; SARAFI M.; ALAVIAN S.M.; ALAVI M.; GOLESTAN SH.; MIKAEILI J.; MALEKZADEH R.

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Journal: GOVARESH JOURNAL Year:2002 | Volume:7 | Issue:37-38 Page(s): 19-26

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Title

CAUSES OF CIRRHOSIS IN A SERIES OF PATIENTS AT A UNIVERSITY HOSPITAL IN TEHRAN

Author(s)

Keywords

CIRRHOSISQ3

AETIOLOGYQ3

HBVQ3

HCVQ3

WILSON'S DISEASEQ4

AUTOIMMUNE HEPATITISQ4

Abstract

Aim: To determine the causes of CIRRHOSIS in Iranian population, and defining the common aetiologies according to patients' sex and age groups. Patients and Methods: 170 patients who were referred to a referral digestive disease centre (Shariati hospital) since 1994-1998 enrolled to a prospective study. All patients had histological and/or clinical and para clinical findings compatible with CIRRHOSIS. Majority of them had complete assessment of history and physical exam oriented for liver disease, liver function tests, abdominal ultrasound and viral serology.Results: Frequency of the causes of liver CIRRHOSIS in our patients (112 M, 58 F, between 7 to 75 years, mean age 44 ± 17.2) were as follow: viral hepatitis type B in 103 patients (60.6%) was the most common cause of CIRRHOSIS, WILSON'S DISEASE found in 15 cases (8.8%), AUTOIMMUNE HEPATITIS in 14 cases (8.2%), alcoholic liver disease in 6 cases (3.5%), Budd-Chiari syndrome in 6 cases (3.5%), hepatitis C virus infection in 6 cases (3.5%), primary biliary CIRRHOSIS in 2 cases (1.2%); secondary biliary CIRRHOSIS; and confection of HBV and HCV each with 3 cases (1.8%). In 10 patients (5.9%) AETIOLOGY of CIRRHOSIS remained unknown.Conclusion: Viral hepatitis B is the most common cause of CIRRHOSIS in Iran. Co-infection of HBV and\HCV is rare. The other causes of liver CIRRHOSIS were WILSON'S DISEASE, AUTOIMMUNE HEPATITIS, alcoholic liver disease, Budd- Chiari syndrome and hepatitis C infection, respectively. WILSON'S DISEASE was the most common cause of CIRRHOSIS in patients less than twenty years of age. Apart from HBV infection that was the most common cause of CIRRHOSIS in both genders, the second AETIOLOGY in male patients was WILSON'S DISEASE and in female patients was AUTOIMMUNE HEPATITIS.

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بررسی تاثیر برنامه خود مراقبتی بر کیفیت زندگی بیماران مبتلا به سیروز کبدی که به مرکز هپاتیت تهران در سال 1381 مراجعه کرده بودند

References

تعیین فراوانی علل ابتلا به هپاتیت مزمن در بیماران مراجعه کنننده به چند مرکز درمانی در شهر تهران

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APA: Copy

AZIMI, K., SARAFI, M., ALAVIAN, S.M., ALAVI, M., GOLESTAN, SH., MIKAEILI, J., & MALEKZADEH, R.. (2002). CAUSES OF CIRRHOSIS IN A SERIES OF PATIENTS AT A UNIVERSITY HOSPITAL IN TEHRAN. GOVARESH JOURNAL, 7(37-38), 19-26. SID. https://sid.ir/paper/86077/en

Vancouver: Copy

AZIMI K., SARAFI M., ALAVIAN S.M., ALAVI M., GOLESTAN SH., MIKAEILI J., MALEKZADEH R.. CAUSES OF CIRRHOSIS IN A SERIES OF PATIENTS AT A UNIVERSITY HOSPITAL IN TEHRAN. GOVARESH JOURNAL[Internet]. 2002;7(37-38):19-26. Available from: https://sid.ir/paper/86077/en

IEEE: Copy

K. AZIMI, M. SARAFI, S.M. ALAVIAN, M. ALAVI, SH. GOLESTAN, J. MIKAEILI, and R. MALEKZADEH, “CAUSES OF CIRRHOSIS IN A SERIES OF PATIENTS AT A UNIVERSITY HOSPITAL IN TEHRAN,” GOVARESH JOURNAL, vol. 7, no. 37-38, pp. 19–26, 2002, [Online]. Available: https://sid.ir/paper/86077/en

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