EPIDEMIOLOGICAL INDICES OF 39 SUBJECTS WITH AUTOIMMUNE HEPATITIS AND THEIR RESPONSE TO TREATMENT IN IRAN

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DARYANI N.E.; MIRMOUMEN SH.; BAHRAMI H.; MOHAMMADI H.R.

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Journal: GOVARESH JOURNAL Year:2001 | Volume:5 | Issue:29-30 Page(s): 135-140

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Title

EPIDEMIOLOGICAL INDICES OF 39 SUBJECTS WITH AUTOIMMUNE HEPATITIS AND THEIR RESPONSE TO TREATMENT IN IRAN

Author(s)

DARYANI N.E. | MIRMOUMEN SH. | BAHRAMI H. | MOHAMMADI H.R. | Issue Writer Certificate

Keywords

AUTOIMMUNE HEPATITISQ4

EPIDEMIOLOGYQ3

TREATMENTQ3

Abstract

Introduction: AUTOIMMUNE HEPATITIS has a wide range of clinical, preclinical and histological manifestations. Our aim was to determine the prevalence of different clinical and preclinical manifestations and response to TREATMENT among Iranian patients with AUTOIMMUNE HEPATITIS.Method and results: 39 patients with the diagnosis of AUTOIMMUNE HEPATITIS according to International AUTOIMMUNE HEPATITIS Group criteria, referred to an outpatient clinic were included. Mean age of the patients was 29.7±15.3 (range 9 to 69 years) and 82% of them were female.Most of the patients were between 15 and 30 years. 23.1% of patients had another autoimmune disease, too. The most common clinical manifestations were fatigue, jaundice and menstrual disturbances, respectively. Most of the patients had abnormalities in liver function tests at diagnosis. 35.9% of the patients were ANA positive, 43.6% ASMA positive and 15.4% of patients had positive ALKM1. Histological evaluations at the time of diagnosis showed that 52.4% of patients had mild, 38.1% moderate and 9.5% had severe inflammation and fibrosis was sever in 28.2% of patients. 71% of patients responded to TREATMENT in two months and 79.3% in 6 months. Complete response was seen in 73% of patients. 17.9% of patients had a relapse of the disease after a complete response.Conclusion: AUTOIMMUNE HEPATITIS in Iranian patients and the response to TREATMENT resemble that in western countries.

Cites

CLINICAL CHARACTERISTICS OF AUTOIMMUNE HEPATITIS

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APA: Copy

DARYANI, N.E., MIRMOUMEN, SH., BAHRAMI, H., & MOHAMMADI, H.R.. (2001). EPIDEMIOLOGICAL INDICES OF 39 SUBJECTS WITH AUTOIMMUNE HEPATITIS AND THEIR RESPONSE TO TREATMENT IN IRAN. GOVARESH JOURNAL, 5(29-30), 135-140. SID. https://sid.ir/paper/86278/en

Vancouver: Copy

DARYANI N.E., MIRMOUMEN SH., BAHRAMI H., MOHAMMADI H.R.. EPIDEMIOLOGICAL INDICES OF 39 SUBJECTS WITH AUTOIMMUNE HEPATITIS AND THEIR RESPONSE TO TREATMENT IN IRAN. GOVARESH JOURNAL[Internet]. 2001;5(29-30):135-140. Available from: https://sid.ir/paper/86278/en

IEEE: Copy

N.E. DARYANI, SH. MIRMOUMEN, H. BAHRAMI, and H.R. MOHAMMADI, “EPIDEMIOLOGICAL INDICES OF 39 SUBJECTS WITH AUTOIMMUNE HEPATITIS AND THEIR RESPONSE TO TREATMENT IN IRAN,” GOVARESH JOURNAL, vol. 5, no. 29-30, pp. 135–140, 2001, [Online]. Available: https://sid.ir/paper/86278/en

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