THE EVALUATION OF LAVENDER AQUEOUS EXTRACT ON HUMAN FIBROBLAST CELLS

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DALILAN S.; HEIDARI KASHL S.; ZAMANIAN AZODI M.; OMIDI R.; ROEINTAN R.; HOSEINI R.

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Journal: JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES Year:2013 | Volume:21 | Issue:1 Page(s): 143-149

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Title

THE EVALUATION OF LAVENDER AQUEOUS EXTRACT ON HUMAN FIBROBLAST CELLS

Author(s)

Keywords

LAVENDER AQUEOUS EXTRACTQ2

FIBROBLASTQ2

MTT ASSAYQ2

CYTOTOXIC EFFECTSQ2

Abstract

Introduction: Application of herbals substances has been prevalent in the treatment of neoplasm diseases such as cancers. Lavender has different biological activates and aqueous extracts of the plant has been shown promising future in the treatment of cancer neurodegenerative diseases.Materials & Methods: The lavender plant and its derivative substances were prepared from the herbarium of Shahid Beheshti University. FIBROBLAST cells were cultured at RPMI 1640 medium (containing 20% fetal bovine serum and 5% CO2 gas at 37oC) to achieve appropriate cell numbers. Microscopic studies were performed in the presents of 100mgml-1 of the extract. MTT ASSAY was applied for cell survival determination in the present of different concentrations of the extract from 0 to 100mgml-1.Findings: Viability test and morphological studies indicated that the population of FIBROBLAST cells decreased significantly at the concentrations of 0 to 100mgml-1 of the lavender extract.Discussion & Conclusion: It could conclude that application of the aqueous extract of lavender should be carry out under certain consideration due to its adverse side effects that might accompany with its effective dosages in cancer therapy. In addition, in vivo studies would be crucial to confirm CYTOTOXIC EFFECTS on cancer and normal cells.

Cites

INVESTIGATION INTO REGENERATION MECHANISM OF HYDROALCOHOLIC LAVENDER (LAVANDULA OFFICIANALIS) EXTRACT THROUGH THE EVALUATION OF NT3 GENE EXPRESSION AFTER SCIATIC NERVE COMPRESSION IN RATS

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APA: Copy

DALILAN, S., HEIDARI KASHL, S., ZAMANIAN AZODI, M., OMIDI, R., ROEINTAN, R., & HOSEINI, R.. (2013). THE EVALUATION OF LAVENDER AQUEOUS EXTRACT ON HUMAN FIBROBLAST CELLS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 21(1), 143-149. SID. https://sid.ir/paper/89844/en

Vancouver: Copy

DALILAN S., HEIDARI KASHL S., ZAMANIAN AZODI M., OMIDI R., ROEINTAN R., HOSEINI R.. THE EVALUATION OF LAVENDER AQUEOUS EXTRACT ON HUMAN FIBROBLAST CELLS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2013;21(1):143-149. Available from: https://sid.ir/paper/89844/en

IEEE: Copy

S. DALILAN, S. HEIDARI KASHL, M. ZAMANIAN AZODI, R. OMIDI, R. ROEINTAN, and R. HOSEINI, “THE EVALUATION OF LAVENDER AQUEOUS EXTRACT ON HUMAN FIBROBLAST CELLS,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 1, pp. 143–149, 2013, [Online]. Available: https://sid.ir/paper/89844/en

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