FUNCTIONALIZATION OF CARBOXYLATED MULTI WALLED NANOTUBES WITH DIAZO COMPOUNDS OF AROMATIC AMINS AND ANTI CANCER STUDY ON SW742 CELL LINE BY INVITRO CONDITIONS

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HEYDARI KESHAL S.; ENTEZARI M.; HEKMATI M.; NASER A.; SOLEIMANI S.

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Journal: Journal of Ilam University of Medical Sciences Year:2013 | Volume:21 | Issue:2 Page(s): 138-143

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Title

FUNCTIONALIZATION OF CARBOXYLATED MULTI WALLED NANOTUBES WITH DIAZO COMPOUNDS OF AROMATIC AMINS AND ANTI CANCER STUDY ON SW742 CELL LINE BY INVITRO CONDITIONS

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Keywords

CARBON NANOTUBEQ2

COLON CENTERQ2

FUNCTIONALIZATIONQ2

Abstract

Introduction: One of the leading causes of death around the world is cancer. Despite the advances in science and technology, man has still failed to cure the disease. The discovery of amazing biological properties of carbon nano tubes caused that they would be good candidates for the research on cancer cells. FUNCTIONALIZATION of CARBON NANOTUBEs is known to improve their properties. Many compounds that have applications in medicinal chemistry have diazo group. In this paper, we tried to functionalize MWNT-COOH with diazo compounds.Materials & Methods: Modification was confirmed by FT-IR, Raman and SEM spectroscopy. The products were tested on colon cancer cells (SW742) by MTT assay. Viability of the colon cancer cells was investtigated in different concentrations of the functionalized products.Findings: The results demonstrated that the viability of cancer cells was profoundly decreased in the presence of the functionnalized nanotubes.Discussion & Conclusion: Our results revealed that the functionalized nanotubes could be a suitable candidate for the synthesis of effective drugs on colon cancer.

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APA: Copy

HEYDARI KESHAL, S., ENTEZARI, M., HEKMATI, M., NASER, A., & SOLEIMANI, S.. (2013). FUNCTIONALIZATION OF CARBOXYLATED MULTI WALLED NANOTUBES WITH DIAZO COMPOUNDS OF AROMATIC AMINS AND ANTI CANCER STUDY ON SW742 CELL LINE BY INVITRO CONDITIONS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 21(2), 138-143. SID. https://sid.ir/paper/90481/en

Vancouver: Copy

HEYDARI KESHAL S., ENTEZARI M., HEKMATI M., NASER A., SOLEIMANI S.. FUNCTIONALIZATION OF CARBOXYLATED MULTI WALLED NANOTUBES WITH DIAZO COMPOUNDS OF AROMATIC AMINS AND ANTI CANCER STUDY ON SW742 CELL LINE BY INVITRO CONDITIONS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2013;21(2):138-143. Available from: https://sid.ir/paper/90481/en

IEEE: Copy

S. HEYDARI KESHAL, M. ENTEZARI, M. HEKMATI, A. NASER, and S. SOLEIMANI, “FUNCTIONALIZATION OF CARBOXYLATED MULTI WALLED NANOTUBES WITH DIAZO COMPOUNDS OF AROMATIC AMINS AND ANTI CANCER STUDY ON SW742 CELL LINE BY INVITRO CONDITIONS,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 2, pp. 138–143, 2013, [Online]. Available: https://sid.ir/paper/90481/en

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