GENETIC POLYMORPHISMS OF CYP2C19 IN THE IRANIAN EPILEPTIC PATIENTS IN COMPARE TO HEALTHY SUBJECTS

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SADRAI SIMA; Nematollahi Hadjar; Salehi Mansur; Zaremehrjerdi Mohammad

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Seminar Paper

Paper Information

Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Year:2013 | Issue:21

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Title

GENETIC POLYMORPHISMS OF CYP2C19 IN THE IRANIAN EPILEPTIC PATIENTS IN COMPARE TO HEALTHY SUBJECTS

Author(s)

SADRAI SIMA | Nematollahi Hadjar | Salehi Mansur | Zaremehrjerdi Mohammad

Keywords

PHARMACOGENETICS

CYP2C19 EPILEPSY

GENETIC

POLYMORPHISM

Abstract

INTRODUCTION THE GENES ENCODING CYP2C19 ARE POLYMORPHICALLY EXPRESSED, WITH THE MOST COMMON * 2 AND * 3, ARE ASSOCIATED WITH DECREASED METABOLISM OF THE RESPECTIVE SUBSTRATES. THE NUCLEOTIDE CHANGES IN THE CYP2C19* 2 AND CYP2C19* 3 ALLELES LEAD TO A SPLICING DEFECT AND STOP CODON RESPECTIVELY, THEREFORE TO DECREASED ENZYME ACTIVITY. …

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APA: Copy

SADRAI, SIMA, Nematollahi, Hadjar, Salehi, Mansur, & Zaremehrjerdi, Mohammad. (2013). GENETIC POLYMORPHISMS OF CYP2C19 IN THE IRANIAN EPILEPTIC PATIENTS IN COMPARE TO HEALTHY SUBJECTS. IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. SID. https://sid.ir/paper/927875/en

Vancouver: Copy

SADRAI SIMA, Nematollahi Hadjar, Salehi Mansur, Zaremehrjerdi Mohammad. GENETIC POLYMORPHISMS OF CYP2C19 IN THE IRANIAN EPILEPTIC PATIENTS IN COMPARE TO HEALTHY SUBJECTS. 2013. Available from: https://sid.ir/paper/927875/en

IEEE: Copy

SIMA SADRAI, Hadjar Nematollahi, Mansur Salehi, and Mohammad Zaremehrjerdi, “GENETIC POLYMORPHISMS OF CYP2C19 IN THE IRANIAN EPILEPTIC PATIENTS IN COMPARE TO HEALTHY SUBJECTS,” presented at the IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. 2013, [Online]. Available: https://sid.ir/paper/927875/en

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