The effectiveness of cathodal transcranial direct current stimulation in patients with obsessive-compulsive disorder

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ENSAFI ELNAZ; ATADOKHT AKBAR; Mikaeeli Niloofar; NARIMANI MOHAMMAD; ROSTAMI REZA

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Journal: JOURNAL OF PSYCHOLOGICAL SCIENCE Year:2019 | Volume:18 | Issue:73 Page(s): 121-131

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Title

The effectiveness of cathodal transcranial direct current stimulation in patients with obsessive-compulsive disorder

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Keywords

Cathodal transcranial direct current stimulationQ1

Obsessive-compulsive disorderQ1

AnxietyQ2

DepressionQ2

Abstract

Background: Obsessive-compulsive disorder (OCD) is one of the disabling disorders associated with extensive personal and social costs. This disorder has a significant comorbidity with Depression and Anxiety disorders, and many of these patients do not respond to psychotherapy and medication. Thus can we develop a new and non-invasive brain stimulation techniques to improve obsessive-compulsive symptoms. Aims: This study aimed to investigate the effectiveness of Cathodal transcranial direct current stimulation (c-tDCS) on obsessive-compulsive, Anxiety, and depressive symptoms in patients with OCD. Method: Thirty OCD patients (15 patients in the experimental group and 15 patients in the placebo group) were selected by convenience sampling. In the intervention step, the experimental group received c-tDCS for 10 sessions (2 sessions per week, 20 minutes each session with 2 mA intensity) and the placebo subjects received the sham-tDCS. Subjects in both groups were evaluated using the Yale-Brown obsessive-compulsive scale(Goodman, 1989), the Hamilton Anxiety rating scale(1959), and the Beck Depression inventory(1978) in the first and tenth sessions. Results: The results of this study showed that the use of c-tDCS in orbitofrontal cortex and anodal transcranial direct current stimulation in O2 region resulted in significant reduction of obsessivecompulsive symptoms (p<0/001), Anxiety (p<0/003), and Depression (p<0/004) in OCD patients. Conclusions: tDCS is an effective non-invasive technique for the improvement of obsessive-compulsive symptoms, Anxiety, and Depression in OCD patients.

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APA: Copy

ENSAFI, ELNAZ, ATADOKHT, AKBAR, Mikaeeli, Niloofar, NARIMANI, MOHAMMAD, & ROSTAMI, REZA. (2019). The effectiveness of cathodal transcranial direct current stimulation in patients with obsessive-compulsive disorder. JOURNAL OF PSYCHOLOGICAL SCIENCE, 18(73 ), 121-131. SID. https://sid.ir/paper/92936/en

Vancouver: Copy

ENSAFI ELNAZ, ATADOKHT AKBAR, Mikaeeli Niloofar, NARIMANI MOHAMMAD, ROSTAMI REZA. The effectiveness of cathodal transcranial direct current stimulation in patients with obsessive-compulsive disorder. JOURNAL OF PSYCHOLOGICAL SCIENCE[Internet]. 2019;18(73 ):121-131. Available from: https://sid.ir/paper/92936/en

IEEE: Copy

ELNAZ ENSAFI, AKBAR ATADOKHT, Niloofar Mikaeeli, MOHAMMAD NARIMANI, and REZA ROSTAMI, “The effectiveness of cathodal transcranial direct current stimulation in patients with obsessive-compulsive disorder,” JOURNAL OF PSYCHOLOGICAL SCIENCE, vol. 18, no. 73 , pp. 121–131, 2019, [Online]. Available: https://sid.ir/paper/92936/en

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