مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

Information Seminar Paper

Title

PHARMACOGENETICS ROLE OF DIHYROPYRIMIDINE DEHYDROGENASE AND THYMIDYLATE SYNTHASE GENES IN FLUOROPYRIMIDINE-BASED CHEMOTHERAPY

Pages

  -

Abstract

 INTRODUCTION & AIM: THE FLUOROPYRIMIDINE DRUG 5-FLUOROURACIL (5-FU) AND THE PRODRUG CAPECITABINE, HAVE BEEN EXTENSIVELY USED FOR TREATMENT OF MANY TYPES OF CANCER INCLUDING COLORECTAL, GASTRIC AND HEAD AND NECK. APPROXIMATELY 10% OF THE PATIENTS SUFFER FROM SEVERE FLUOROPYRIMIDINE-INDUCED TOXICITY, LIKE DIARRHEA, MUCOSITIS, MYELOSUPPRESSION AND HAND-FOOT SYNDROME. THIS MAY LEAD TO DOSE REDUCTION AND TREATMENT DISCONTINUATION. PHARMACOGENETICS RESEARCH COULD BE USEFUL FOR IDENTIFICATION OF PREDICTIVE MARKERS IN CHEMOTHERAPY TREATMENT...

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    • Cite

    APA: Copy

    Abasian, Mohamad Hadi, Ansarinejad, Nafiseh, ABBASI, BAHAREH, RAMIM, TAYEB, & ARDEKANI, ALI M.. (2016). PHARMACOGENETICS ROLE OF DIHYROPYRIMIDINE DEHYDROGENASE AND THYMIDYLATE SYNTHASE GENES IN FLUOROPYRIMIDINE-BASED CHEMOTHERAPY. INTERNATIONAL GASTROINTESTINAL CANCER CONGRESS. SID. https://sid.ir/paper/936320/en

    Vancouver: Copy

    Abasian Mohamad Hadi, Ansarinejad Nafiseh, ABBASI BAHAREH, RAMIM TAYEB, ARDEKANI ALI M.. PHARMACOGENETICS ROLE OF DIHYROPYRIMIDINE DEHYDROGENASE AND THYMIDYLATE SYNTHASE GENES IN FLUOROPYRIMIDINE-BASED CHEMOTHERAPY. 2016. Available from: https://sid.ir/paper/936320/en

    IEEE: Copy

    Mohamad Hadi Abasian, Nafiseh Ansarinejad, BAHAREH ABBASI, TAYEB RAMIM, and ALI M. ARDEKANI, “PHARMACOGENETICS ROLE OF DIHYROPYRIMIDINE DEHYDROGENASE AND THYMIDYLATE SYNTHASE GENES IN FLUOROPYRIMIDINE-BASED CHEMOTHERAPY,” presented at the INTERNATIONAL GASTROINTESTINAL CANCER CONGRESS. 2016, [Online]. Available: https://sid.ir/paper/936320/en

    Related Journal Papers

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    • Related Plans

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