The Effect of Cryotherapy Spray with Fluticasone on Tissue Repair after Endoscopic Sinus Surgery in Patients with Nasal Polyposis: A Randomized Clinical Trial Study

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REZAEIAN AHMAD; HASHEMI SEYED MOSTAFA; Rasekh Farshid

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Journal Paper

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Journal: Journal of Isfahan Medical School Year:2020 | Volume:38 | Issue:586 Page(s): 563-568

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Title

The Effect of Cryotherapy Spray with Fluticasone on Tissue Repair after Endoscopic Sinus Surgery in Patients with Nasal Polyposis: A Randomized Clinical Trial Study

Author(s)

REZAEIAN AHMAD | HASHEMI SEYED MOSTAFA | Rasekh Farshid | Issue Writer Certificate

Keywords

Cryotherapy

Fluticasone

Endoscopy

Sinus

Abstract

Background: Recently, spray Cryotherapy has been used in otorhinolaryngology surgeries. Therefore, due to limited studies in this field, this study aimed to evaluate the effect of spray Cryotherapy on tissue repair after endoscopic Sinus surgery in patients with nasal polyposis, and compare this method with Fluticasone and normal saline spray. Methods: In this clinical trial study, 45 patients with nasal polyps were enrolled according to the inclusion criteria of the study. Then, the patients were randomly assigned into three equal groups. The first group was treated with spray Cryotherapy, the second group was treated with Fluticasone spray, and the third group received normal saline spray after the operation with four puffs for each group. It should be noted that Fluticasone spray was maintained for two weeks after surgery for the three groups. Subsequently, the results of this study were evaluated using Sino-nasal Outcome Test (SNOT-22) questionnaire at intervals of one and three months after the surgical operation. Findings: The mean SNOT-22 score after the surgery significantly decreased in the three groups. There was a significant difference between the three groups concerning the SNOT-22 scores at intervals of one and three months after the surgery, as the SNOT-22 score in the Cryotherapy group was lower than the other groups (P < 0. 05). Conclusion: Using spray Cryotherapy is a safe and effective method after endoscopic Sinus surgery compared to the corticosteroid and normal saline spray.

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APA: Copy

REZAEIAN, AHMAD, HASHEMI, SEYED MOSTAFA, & Rasekh, Farshid. (2020). The Effect of Cryotherapy Spray with Fluticasone on Tissue Repair after Endoscopic Sinus Surgery in Patients with Nasal Polyposis: A Randomized Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 38(586 ), 563-568. SID. https://sid.ir/paper/952202/en

Vancouver: Copy

REZAEIAN AHMAD, HASHEMI SEYED MOSTAFA, Rasekh Farshid. The Effect of Cryotherapy Spray with Fluticasone on Tissue Repair after Endoscopic Sinus Surgery in Patients with Nasal Polyposis: A Randomized Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2020;38(586 ):563-568. Available from: https://sid.ir/paper/952202/en

IEEE: Copy

AHMAD REZAEIAN, SEYED MOSTAFA HASHEMI, and Farshid Rasekh, “The Effect of Cryotherapy Spray with Fluticasone on Tissue Repair after Endoscopic Sinus Surgery in Patients with Nasal Polyposis: A Randomized Clinical Trial Study,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 38, no. 586 , pp. 563–568, 2020, [Online]. Available: https://sid.ir/paper/952202/en

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