The Sensory-Motor Changes in Patients Undergoing Lower Limb Orthopedic Surgery with Spinal Anesthesia by Two Drug Combinations of Ropivacaine Plus Dexmedetomidine and Ropivacaine Plus Fentanyl: A Clinical Trial Study

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Talakoub Reyhanak; HASHEMI SEYED TAGHI; HOSEINI MOHAMMAD JAVAD

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2020 | Volume:38 | Issue:585 Page(s): 537-544

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Title

The Sensory-Motor Changes in Patients Undergoing Lower Limb Orthopedic Surgery with Spinal Anesthesia by Two Drug Combinations of Ropivacaine Plus Dexmedetomidine and Ropivacaine Plus Fentanyl: A Clinical Trial Study

Author(s)

Talakoub Reyhanak | HASHEMI SEYED TAGHI | HOSEINI MOHAMMAD JAVAD | Issue Writer Certificate

Keywords

Dexmedetomidine

Ropivacaine

Fentanyl

Nerve block

Postoperative pain

Abstract

Background: The present study aimed to evaluate the sensory-motor changes in patients undergoing lower limb orthopedic surgery with spinal anesthesia by two drug combinations of Ropivacaine plus Dexmedetomidine and Ropivacaine plus Fentanyl. Methods: In a clinical trial study, 90 patients underwent lower extremity orthopedic surgery with spinal anesthesia were selected and randomly allocated in three groups of 30. In the first group, 4. 5 ml of Ropivacaine 0. 5% isobaric plus 5 micrograms of Dexmedetomidine in 0. 5 cc of distilled water, in the second group, 4. 5 cc of isobaric Ropivacaine plus 25 micrograms of Fentanyl in 0. 5 cc distillated water, and in the third group, 4. 5 ml Ropivacaine 0. 5% isobaric in 0. 5 cc distillated water was injected. The severity of pain and sensory and motor characteristics of patients were determined and compared between the three groups. Findings: The mean time of onset of sensory motor block in the three groups of Ropivacaine-Dexmedetomidine, Ropivacaine-Fentanyl and Ropivacaine alone was 9. 1 ± 3. 0, 11. 2 ± 3. 2, and 12. 5 ± 4. 3 minutes, respectively (P = 0. 001). The mean time of motor block in the three groups was 10. 9 ± 3. 3, 14. 7 ± 5. 1, and 15. 8 ± 4. 8 minutes, and this time was shorter in the groups of Ropivacaine-Dexmedetomidine (P < 0. 001). Conclusion: The onset of sensory and motor block was shorter in the Ropivacaine-Dexmedetomidine group.

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APA: Copy

Talakoub, Reyhanak, HASHEMI, SEYED TAGHI, & HOSEINI, MOHAMMAD JAVAD. (2020). The Sensory-Motor Changes in Patients Undergoing Lower Limb Orthopedic Surgery with Spinal Anesthesia by Two Drug Combinations of Ropivacaine Plus Dexmedetomidine and Ropivacaine Plus Fentanyl: A Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 38(585 ), 537-544. SID. https://sid.ir/paper/952844/en

Vancouver: Copy

Talakoub Reyhanak, HASHEMI SEYED TAGHI, HOSEINI MOHAMMAD JAVAD. The Sensory-Motor Changes in Patients Undergoing Lower Limb Orthopedic Surgery with Spinal Anesthesia by Two Drug Combinations of Ropivacaine Plus Dexmedetomidine and Ropivacaine Plus Fentanyl: A Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2020;38(585 ):537-544. Available from: https://sid.ir/paper/952844/en

IEEE: Copy

Reyhanak Talakoub, SEYED TAGHI HASHEMI, and MOHAMMAD JAVAD HOSEINI, “The Sensory-Motor Changes in Patients Undergoing Lower Limb Orthopedic Surgery with Spinal Anesthesia by Two Drug Combinations of Ropivacaine Plus Dexmedetomidine and Ropivacaine Plus Fentanyl: A Clinical Trial Study,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 38, no. 585 , pp. 537–544, 2020, [Online]. Available: https://sid.ir/paper/952844/en

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