Study some of hepatic parameters following exposure to 67gallium and 131 iodine in male rat

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Dadfar Fereshteh; BAMDAD KOUROSH; JAFARI SOMAYEH

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Journal Paper

Paper Information

Journal: Pars Journal of Medical Sciences Year:2019 | Volume:17 | Issue:2 Page(s): 40-45

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Title

Study some of hepatic parameters following exposure to 67gallium and 131 iodine in male rat

Author(s)

Dadfar Fereshteh | BAMDAD KOUROSH | JAFARI SOMAYEH | Issue Writer Certificate

Keywords

131Iodine

67Gallium

Hepatic Enzymes

Hepatic Proteins

Abstract

Introduction: The liver is an organ at risk in radiotherapy of thoracic and abdominal tumors. In this study was investigated the alteration in liver functional tests during radiotherapy with gallium 67 and iodine 131. Materials & Methods: Sixty male Wistar rats were divided into 3 groups: the control without treatment, the experimental groups 1 and 2 received 0. 1Mci 131 iodine through oral gavage 0. 3Mci 67Gallium with intraperitoneal injection respectively. 48 hours after injection or oral gavage, the level of serum aspartate aminotransferase, alanine aminotransferase and albumin were checked. Results: The results showed that level of serum aspartate aminotransferase in 131 iodine group and alanine aminotransferase and albumin significant increase in 131 iodine and 67Gallium than control group. Conclusion: Regarding liver sensitivity during radiation therapy and elevated serum levels of these enzymes, liver function tests may be useful as biomarkers for the detection of radiotherapy effects.

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APA: Copy

Dadfar, Fereshteh, BAMDAD, KOUROSH, & JAFARI, SOMAYEH. (2019). Study some of hepatic parameters following exposure to 67gallium and 131 iodine in male rat. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), 17(2 ), 40-45. SID. https://sid.ir/paper/952945/en

Vancouver: Copy

Dadfar Fereshteh, BAMDAD KOUROSH, JAFARI SOMAYEH. Study some of hepatic parameters following exposure to 67gallium and 131 iodine in male rat. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL)[Internet]. 2019;17(2 ):40-45. Available from: https://sid.ir/paper/952945/en

IEEE: Copy

Fereshteh Dadfar, KOUROSH BAMDAD, and SOMAYEH JAFARI, “Study some of hepatic parameters following exposure to 67gallium and 131 iodine in male rat,” PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), vol. 17, no. 2 , pp. 40–45, 2019, [Online]. Available: https://sid.ir/paper/952945/en

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