the Effect of Vitamin C on Atrial Fibrillation in Patients Underwent Coronary Artery Surgery; A Randomized Clinical Trial Study

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PAZOKI ALI; Daei Mohammad Mahdi; Azarasa Mitra; DODANGEH SAMIRA; Mehrdel Roghayeh; CHANGIZI ALI

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2021 | Volume:39 | Issue:614 Page(s): 107-113

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Title

the Effect of Vitamin C on Atrial Fibrillation in Patients Underwent Coronary Artery Surgery; A Randomized Clinical Trial Study

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Keywords

Atrial fibrillation

Coronary artery bypass

Ascorbic acid

Abstract

Background: One of the most common cardiac arrhythmias after Coronary artery bypass graft surgery is Atrial fibrillation, and its occurrence is associated with an increase in the length of hospitalization morbidity and postoperative mortality. Recently, the role of oxidative stress in the pathophysiology of this arrhythmia has been raised. Current research was done to assess the role of prescribing vitamin C in preventing this arrhythmia. Methods: In this clinical trial study, 140 patients who underwent Coronary artery bypass graft surgery in Booali hospital, Qazvin, Iran, in the years 2016 to 2017 were randomly divided into two equal case and control groups. The case group received 1 g of vitamin C per day from 24 hours prior to 48 hours after surgery, and the control group received placebo at same time. Finally, data were analyzed using SPSS software, and incidence of postoperative Atrial fibrillation was compared between the two groups. Findings: Of 140 studied patients, 4 cases (5. 7%) of the case group and 11 cases (15. 71%) of control group had Atrial fibrillation, and the difference between the two groups was significant (P = 0. 028). Conclusion: Our study showed that administration of oral vitamin C can effectively reduce the incidence of Atrial fibrillation after Coronary artery bypass graft surgery.

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APA: Copy

PAZOKI, ALI, Daei, Mohammad Mahdi, Azarasa, Mitra, DODANGEH, SAMIRA, Mehrdel, Roghayeh, & CHANGIZI, ALI. (2021). the Effect of Vitamin C on Atrial Fibrillation in Patients Underwent Coronary Artery Surgery; A Randomized Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 39(614 ), 107-113. SID. https://sid.ir/paper/953716/en

Vancouver: Copy

PAZOKI ALI, Daei Mohammad Mahdi, Azarasa Mitra, DODANGEH SAMIRA, Mehrdel Roghayeh, CHANGIZI ALI. the Effect of Vitamin C on Atrial Fibrillation in Patients Underwent Coronary Artery Surgery; A Randomized Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2021;39(614 ):107-113. Available from: https://sid.ir/paper/953716/en

IEEE: Copy

ALI PAZOKI, Mohammad Mahdi Daei, Mitra Azarasa, SAMIRA DODANGEH, Roghayeh Mehrdel, and ALI CHANGIZI, “the Effect of Vitamin C on Atrial Fibrillation in Patients Underwent Coronary Artery Surgery; A Randomized Clinical Trial Study,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 39, no. 614 , pp. 107–113, 2021, [Online]. Available: https://sid.ir/paper/953716/en

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