The Effect of High-Intensity Interval Training on GLP-1, Appetite, and Weight in Obese Rats

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Sepehri Mohammad Hossein; NEMATI JAVAD; Koushkie Jahromi Maryam; Eskandai Mohammad Hadi; DARYANOOSH FARHAD

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Journal: Jundishapur Scientific Medical Journal Year:2021 | Volume:20 | Issue:3 Page(s): 290-299

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Title

The Effect of High-Intensity Interval Training on GLP-1, Appetite, and Weight in Obese Rats

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Keywords

High-intensity interval training

Appetite

GLP-1

Weight

Abstract

Background and Objectives: Appetite is an essential factor in obesity. The present study aimed to evaluate the effect of High-intensity interval training (HIIT) on GLP-1, Appetite, and Weight of obese mice while maintaining a high caloric diet. Subjects and Methods A total of 24 C57BL/6 mice with a Mean± SD Weight of 20. 7± 1 g were selected. After implementing a high caloric dieting and making them fat (Mean± SD Weight: 30. 95± 3. 23 g), they were divided into two groups of training and control. A high caloric diet was maintained for both groups (training and control) until the end of the experiment, while the training group performed HIIT for 8 weeks. Every session of HIIT included 30 minutes of exercise with a progressive intensity of 50% to 60% in low-intensity intervals and 80% to 90% in high-intensity intervals. The independent t test and analysis of variance with repeated measures were used for data analysis. Results Findings of the study indicated that GLP-1 increased significantly in the HIIT training group compared to the control group (P<0. 05). In the HIIT group, body Weight was significantly higher (P<0. 001), and food intake was significantly lower (P<0. 001) than those in the control group. Conclusion When consuming high-calorie food, HIIT training can probably cause Weight loss through reducing Appetite mediated by increasing GLP-1.

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APA: Copy

Sepehri, Mohammad Hossein, NEMATI, JAVAD, Koushkie Jahromi, Maryam, Eskandai, Mohammad Hadi, & DARYANOOSH, FARHAD. (2021). The Effect of High-Intensity Interval Training on GLP-1, Appetite, and Weight in Obese Rats. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 20(3 ), 290-299. SID. https://sid.ir/paper/953837/en

Vancouver: Copy

Sepehri Mohammad Hossein, NEMATI JAVAD, Koushkie Jahromi Maryam, Eskandai Mohammad Hadi, DARYANOOSH FARHAD. The Effect of High-Intensity Interval Training on GLP-1, Appetite, and Weight in Obese Rats. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2021;20(3 ):290-299. Available from: https://sid.ir/paper/953837/en

IEEE: Copy

Mohammad Hossein Sepehri, JAVAD NEMATI, Maryam Koushkie Jahromi, Mohammad Hadi Eskandai, and FARHAD DARYANOOSH, “The Effect of High-Intensity Interval Training on GLP-1, Appetite, and Weight in Obese Rats,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 20, no. 3 , pp. 290–299, 2021, [Online]. Available: https://sid.ir/paper/953837/en

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